Protein Alignment B52 and Srsf3

DIOPT Version :10

• Sequence 1: NP_788671.2
• Gene: B52 / 41670
• FlyBaseID: FBgn0004587
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_038691.1
• Gene: Srsf3 / 20383
• MGIID: 98285
• Length: 164
• Species: Mus musculus
• Alignment Length: 287
• Identity: 77/287 - (26%)
• Similarity: 93/287 - (32%)
• Gaps: 137/287 - (47%)

  Fly     5 RVYVGGLPYGVRERDLERFFKGYGRTRDILIKN---GYGFVEFEDYRDADDAVYELNGKELLGER 66
            :||||.|.....:.:|||.|..||..|.:.:..   |:.||||||.|||.|||.||:|:.|.|.|
Mouse    11 KVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCR 75

  Fly    67 VVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVENLSSRV 131
            |.||.:.|..|..||                               |||               .
Mouse    76 VRVELSNGEKRSRNR-------------------------------GPP---------------P 94

  Fly   132 SWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVEDRRGGR 196
            ||
Mouse    95 SW--------------------------------------------------------------- 96

  Fly   197 SGGGGGSGRGRSRSSSSRSRSRSRRRSRSRRSSHSRSKSRSRSKSRGGRSKSKSPVKSRSRSRSR 261
                     ||......|.||...||...||.|.|||:|||.|:.|.         :.||.||.|
Mouse    97 ---------GRRPRDDYRRRSPPPRRRSPRRRSFSRSRSRSLSRDRR---------RERSLSRER 143

  Fly   262 SNKSRDVSKSKSKSHSRTRSRSPKRER 288
            ::|       .|:|.||:||||...||
Mouse   144 NHK-------PSRSFSRSRSRSRSNER 163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_788671.2	RRM1_SRSF4_like	5..74	CDD:409774	34/71 (48%)
		RRM2_SRSF4_like	120..191	CDD:410012	2/70 (3%)
Srsf3	NP_038691.1	Sufficient for interaction with NXF1 and SRSP. /evidence=ECO:0000250|UniProtKB:P84103	1..90		36/78 (46%)
		RRM_SRSF3	6..86	CDD:241089	35/74 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	81..164		43/217 (20%)
		2 X approximate repeats, basic	119..164		25/61 (41%)