DRSC/TRiP Functional Genomics Resources

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Protein Alignment B52 and Rbmxl1

DIOPT Version :10

Sequence 1:NP_788671.2 Gene:B52 / 41670 FlyBaseID:FBgn0004587 Length:355 Species:Drosophila melanogaster
Sequence 2:NP_033059.2 Gene:Rbmxl1 / 19656 MGIID:1343045 Length:388 Species:Mus musculus


Alignment Length:433 Identity:108/433 - (24%)
Similarity:140/433 - (32%) Gaps:147/433 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 RVYVGGLPYGVRERDLERFFKGYGRTRDILI--------KNGYGFVEFEDYRDADDAVYELNGKE 61
            ::::|||.....|:.||..|..|||..:||:        ..|:.||.||...||.||..::|||.
Mouse     9 KLFIGGLNTETNEKALEAVFGKYGRIVEILLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKS 73

  Fly    62 LLGERVVVE----------------------PARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNK 104
            |.|:.:.||                      |.||...||...|.....||....||...|....
Mouse    74 LDGKAIKVEQATKPSFESGRRGPPPPPRSRGPPRGLRGGSGGTRGPPSRGGYMDDGGYSMNFNMS 138

  Fly   105 NS----------------------------RSSS-------------RYGPPLRTE--------- 119
            :|                            ||||             .||.|.|.|         
Mouse   139 SSRGPLPVKRGPPPRSGGPPPKRSTPSGPVRSSSGMGGRTPVSRGRDSYGGPPRREPLPSRRDVY 203

  Fly   120 -------YRLIVENLSSR--VSWQDLKDYMRQAGEVTYAD-AHKQRRNEGVVEFASLSDMKTAIE 174
                   |. ..::.|||  .|.:|.:||.....:.||.| :|...|:    ::.|         
Mouse   204 LSPRDDGYS-TKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYSHSSSRD----DYPS--------- 254

  Fly   175 KLDDTELNGRRIHLVEDRRGGRSGGGGGSGRGRSRSSSSRSRSRSRRRS-RSRRSSHSRSKSRSR 238
                                  .|.|...|.||.|..|......|.|.| .|..:|.|...:|..
Mouse   255 ----------------------RGYGDRDGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPPTRGP 297

  Fly   239 SKSRGGRSKSKSPVKSRSRSRSRSNKSRD-VSKSKSKSHSRTRSRSPKRERDSRSRSRSVSKRES 302
            ..|.||.|:    ....|.||.....||| .|.|:|..:|..|.|..::||..           .
Mouse   298 PPSYGGSSR----YDDYSSSRDGYGGSRDSYSSSRSDLYSSGRDRVGRQERGL-----------P 347

  Fly   303 RSRSRSKSIHRDSRSRDRSASAENKSRSRSRSRSASPKNGNAS 345
            .|..|.....|||    .|:|:....|...|..|.|.:.|..|
Mouse   348 PSMERGYPPPRDS----YSSSSRGAPRGGGRGGSRSDRGGGRS 386

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
B52NP_788671.2 RRM1_SRSF4_like 5..74 CDD:409774 29/98 (30%)
RRM2_SRSF4_like 120..191 CDD:410012 14/73 (19%)
Rbmxl1NP_033059.2 RRM_RBMX_like 7..86 CDD:409816 28/76 (37%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 59..388 91/383 (24%)
RBM1CTR 170..214 CDD:400429 9/44 (20%)

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