Protein Alignment B52 and Ncl

DIOPT Version :10

• Sequence 1: NP_788671.2
• Gene: B52 / 41670
• FlyBaseID: FBgn0004587
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_035010.3
• Gene: Ncl / 17975
• MGIID: 97286
• Length: 707
• Species: Mus musculus
• Alignment Length: 257
• Identity: 67/257 - (26%)
• Similarity: 94/257 - (36%)
• Gaps: 75/257 - (29%)

  Fly     8 VGGLPYGVRERDLERFFKGYGRTRDILIK---------NGYGFVEFEDYRDADDAVYELNGKELL 63
            :..|.|...:..||..|:     :...||         .||.|:||..:.||.:|:...|..|:.
Mouse   491 LSNLSYSATKETLEEVFE-----KATFIKVPQNPHGKPKGYAFIEFASFEDAKEALNSCNKMEIE 550

  Fly    64 GERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVENLS 128
            |..:.:|     .:||                         ||||.     |.:|   |.|:.||
Mouse   551 GRTIRLE-----LQGS-------------------------NSRSQ-----PSKT---LFVKGLS 577

  Fly   129 SRVSWQDLKDYMR---QAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHL-- 188
            ...:.:.||:...   :|..||..:.... :..|.|:|.|..|.|.|.|.::|.|::|.::.|
Mouse   578 EDTTEETLKESFEGSVRARIVTDRETGSS-KGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDW 641

  Fly   189 ----VEDRRGGRSGGGGG-SGRGRSRSSSSRSRSRSRRRSRSRRSSHSRSKSRSRSKSRGGR 245
                .|...|||.||.|| .|||..|.            .|.......|.....|...||||
Mouse   642 AKPKGEGGFGGRGGGRGGFGGRGGGRG------------GRGGFGGRGRGGFGGRGGFRGGR 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_788671.2	RRM1_SRSF4_like	5..74	CDD:409774	19/74 (26%)
		RRM2_SRSF4_like	120..191	CDD:410012	21/79 (27%)
Ncl	NP_035010.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..308
		PRK13808	<12..142	CDD:172341
		8 X 8 AA tandem repeats of X-T-P-X-K-K-X-X	58..135
		RRM1_NCL	309..383	CDD:409837
		RRM2_NCL	392..467	CDD:409838
		RRM3_NCL	486..558	CDD:409839	19/76 (25%)
		RRM4_NCL	569..646	CDD:409840	22/80 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	639..707		20/65 (31%)