Protein Alignment B52 and CIRBP

DIOPT Version :10

• Sequence 1: NP_788671.2
• Gene: B52 / 41670
• FlyBaseID: FBgn0004587
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_001287758.1
• Gene: CIRBP / 1153
• HGNCID: 1982
• Length: 297
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 68/281 - (24%)
• Similarity: 92/281 - (32%)
• Gaps: 123/281 - (43%)

  Fly     5 RVYVGGLPYGVRERDLERFFKGYGRTRDILI--------KNGYGFVEFEDYRDADDAVYELNGKE 61
            :::||||.:...|:.||:.|..||:..::::        ..|:|||.||:..||.||:..:|||.
Human     7 KLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKS 71

  Fly    62 LLGERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVEN 126
            :.|.::.|:.|..::        |:|..|.|||..|
Human    72 VDGRQIRVDQAGKSS--------DNRSRGYRGGSAG----------------------------- 99

  Fly   127 LSSRVSWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVED 191
                                                                    ||...
Human   100 --------------------------------------------------------GRGFF---- 104

  Fly   192 RRGGRSGGGGGSGRGRSRSSSSRSRSRSRRRSRSRRSSHSRSKSRSRSKSRGGRSKSKSPVKSRS 256
             ||||     |.|||.||....|....:|..|||.....||....|||:| ||.|
Human   105 -RGGR-----GRGRGFSRGGGDRGYGGNRFESRSGGYGGSRDYYSSRSQS-GGYS---------- 152

  Fly   257 RSRSRSNKSRDVSKSKSKSHS 277
             .||.....||...|..||||
Human   153 -DRSSGGSYRDSYDSYGKSHS 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_788671.2	RRM1_SRSF4_like	5..74	CDD:409774	26/76 (34%)
		RRM2_SRSF4_like	120..191	CDD:410012	2/70 (3%)
CIRBP	NP_001287758.1	RRM_CIRBP_RBM3	6..85	CDD:409883	26/77 (34%)