Protein Alignment B52 and SNRNP35

DIOPT Version :9

• Sequence 1: NP_001014619.2
• Gene: B52 / 41670
• FlyBaseID: FBgn0004587
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_851030.1
• Gene: SNRNP35 / 11066
• HGNCID: 30852
• Length: 251
• Species: Homo sapiens
• Alignment Length: 334
• Identity: 65/334 - (19%)
• Similarity: 94/334 - (28%)
• Gaps: 172/334 - (51%)

  Fly     6 VYVGGLPYGVRERDLERFFKGYG------RTRDIL--IKNGYGFVEFED-------YRDADDAV- 54
            ::|..|....:|..|:..|..||      ..||::  ...||.|:|:::       |||||..|
Human    58 LFVARLNLQTKEDKLKEVFSRYGDIRRLRLVRDLVTGFSKGYAFIEYKEERAVIKAYRDADGLVI 122

  Fly    55 --------YELNGKELLGERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSR 111
                    |||       ||        |.:|....|.....||::..|..|:..:::
Human   123 DQHEIFVDYEL-------ER--------TLKGWIPRRLGGGLGGKKESGQLRFGGRDR------- 165

  Fly   112 YGPPLRTEYRL-IVENLSSRVSWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEK 175
               |.|....| :|:|        ||           |.:..::|
Human   166 ---PFRKPINLPVVKN--------DL-----------YREGKRER-------------------- 188

  Fly   176 LDDTELNGRRIHLVEDRRGGRSGGGGGSGRGRSRSSSSRSRSRSRRRSRSRRSSHSRSKSRSRSK 240
                                                  |.|||||.|       |..|::|.|..
Human   189 --------------------------------------RERSRSRER-------HWDSRTRDRDH 208

  Fly   241 SRGGRSKSKSPVKSRSRSRSRSNKSRDVSKSKSKSHSRTRSRSPKR-------ERDSRSRSRSVS 298
            .| ||.|                              |.:.|.|.|       ||:...|...:.
Human   209 DR-GREK------------------------------RWQEREPTRVWPDNDWERERDFRDDRIK 242

  Fly   299 KRESRSRSR 307
            .||.:.|.:
Human   243 GREKKERGK 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_001014619.2	RRM1_SRSF4_like	5..74	CDD:240783	24/91 (26%)
		RRM2_SRSF4_like	120..191	CDD:241044	7/71 (10%)
SNRNP35	NP_851030.1	RRM_snRNP35	53..142	CDD:240683	26/98 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900