Protein Alignment B52 and SRSF10

DIOPT Version :10

• Sequence 1: NP_788671.2
• Gene: B52 / 41670
• FlyBaseID: FBgn0004587
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_473357.1
• Gene: SRSF10 / 10772
• HGNCID: 16713
• Length: 262
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 99/347 - (28%)
• Similarity: 154/347 - (44%)
• Gaps: 110/347 - (31%)

  Fly     6 VYVGGLPYGVRERDLERFFKGYGRTRDILI--------KNGYGFVEFEDYRDADDAVYELNGKEL 62
            ::|..:....|..||.|.|..||...|:.:        ..|:.:|:|||.|||:||::.|:.|.:
Human    12 LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWI 76

  Fly    63 LGERVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVENL 127
            .|.::.::.|:|..:..|:.:..:   ||......||::.::..||.||
Human    77 CGRQIEIQFAQGDRKTPNQMKAKE---GRNVYSSSRYDDYDRYRRSRSR---------------- 122

  Fly   128 SSRVSWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSDMKTAIEKLDDTELNGRRIHLVEDR 192
                                   ::::||:                 :....:.|.||.:...:.
Human   123 -----------------------SYERRRS-----------------RSRSFDYNYRRSYSPRNS 147

  Fly   193 RGGRSGGGGGSGR-GRSRSSSSRSRSRSRRRSRSRRSSHSRSKSRSRSKSRGGRSKSKSPVKSRS 256
            |        .:|| .||||.|...|.:.|.||.||    |:|.||||||     |:.|..:|::|
Human   148 R--------PTGRPRRSRSHSDNDRFKHRNRSFSR----SKSNSRSRSK-----SQPKKEMKAKS 195

  Fly   257 RSRSRSN-KSRDVSKSKSKSHSRTRSRSPKRERDSRSRSRSVSKRESRSRSRSKSIHRDSRSRDR 320
            ||||.|: |:|..||:.||:|.::.||   .|::||.:....||.:|||:||
Human   196 RSRSASHTKTRGTSKTDSKTHYKSGSR---YEKESRKKEPPRSKSQSRSQSR------------- 244

  Fly   321 SASAENKSRSRSRSRS-ASPKN 341
                   |||:||||| .|||:
Human   245 -------SRSKSRSRSWTSPKS 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B52	NP_788671.2	RRM1_SRSF4_like	5..74	CDD:409774	23/75 (31%)
		RRM2_SRSF4_like	120..191	CDD:410012	5/70 (7%)
SRSF10	NP_473357.1	RRM_SF	5..99	CDD:473069	25/86 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..262		70/240 (29%)