DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp4 and PAB1

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_174676.2	Gene:	PAB1 / 840313	AraportID:	AT1G34140	Length:	407	Species:	Arabidopsis thaliana

Alignment Length:	309	Identity:	75/309 - (24%)
Similarity:	125/309 - (40%)	Gaps:	58/309 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVDPK-SVEIVQRARPHTI 97
            :::..|....|...|:..|.:||.:..|||::|. ...||.||||.:...: :|..:::.....:
plant   121 VYVKNLVETATDADLKRLFGEFGEITSAVVMKDG-EGKSRRFGFVNFEKAEAAVTAIEKMNGVVV 184

  Fly    98 DNKIVETKHALPR----QDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYHDENIVREYFSQ 158
            |.|.:....|..:    :|.|....:..::.......| ||   :::..|.:..|...:.|.||:
plant   185 DEKELHVGRAQRKTNRTEDLKAKFELEKIIRDMKTRKG-MN---LYVKNLDDSVDNTKLEELFSE 245

  Fly   159 FGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKAL----------APRKHWILQTLVEVKRSTQ 213
            ||.:.|.|::: ...|..:..||:||.....|.||:          .|    |..:|.:.|.. .
plant   246 FGTITSCKVMV-HSNGISKGVGFVEFSTSEEASKAMLKMNGKMVGNKP----IYVSLAQCKEQ-H 304

  Fly   214 KADRRFRF----------PIFSSVRAGYIPPQPATADSYN--YNNPNYNPY-LAQSVLPPSAFTN 265
            |...:.:|          ||||.|.|      |||..|..  ....|:.|| :..|.:|.|....
plant   305 KLHLQTQFNNPPPSPHQQPIFSQVVA------PATMLSQQTPLRGYNFQPYSMCGSRMPNSCPPI 363

  Fly   266 GWAHYVIPMAPKPT-----PGQNMAASLPSQQLAEHSLNGHGPDMWSSY 309
            ...::::|...:||     |...:..|||...|.        |::|:.|
plant   364 SIPNFMVPQPFRPTLYPPAPLVGLYGSLPQPLLQ--------PNLWNPY 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	20/76 (26%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	20/81 (25%)
PAB1	NP_174676.2	RRM_SF	<1..23	CDD:302621
		RRM2_I_PABPs	29..105	CDD:240825
		ELAV_HUD_SF	30..296	CDD:273741	44/184 (24%)
		RRM3_I_PABPs	118..197	CDD:240826	20/76 (26%)
		RRM4_I_PABPs	222..299	CDD:240827	23/85 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910