DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp4 and Hnrnpab

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	XP_006246407.1	Gene:	Hnrnpab / 83498	RGDID:	69255	Length:	332	Species:	Rattus norvegicus

Alignment Length:	338	Identity:	90/338 - (26%)
Similarity:	141/338 - (41%)	Gaps:	76/338 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ASSACLGDCKGDGKTAIKEEGYEHLRKIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNH 71
            |.|......:||...|.|.|  |...|:|:||||..|:.:.|:.:|::||.|.|..:..||.:..
  Rat    52 APSGNQNGAEGDQINASKNE--EDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGR 114

  Fly    72 SRGFGFVTYVDPKSVEIVQRARPHTIDNKIVETKHALP-RQDFKRGGGVGSVVGSFGCEAGFMNS 135
            ||||||:.:.|..|||.|...:.|.:|.::::.|.|:. ::|                     ..
  Rat   115 SRGFGFILFKDSSSVEKVLDQKEHRLDGRVIDPKKAMAMKKD---------------------PV 158

  Fly   136 KRIFLGGLKEYHDENIVREYFSQFGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAPRKHW 200
            |:||:|||.....|..:||||.|||.:.:::|.:|.:..::|.|.|:.|.:....:|.|..:.|.
  Rat   159 KKIFVGGLNPEATEEKIREYFGQFGEIEAIELPIDPKLNKRRGFVFITFKEEDPVKKVLEKKFHT 223

  Fly   201 ILQTLVEVKRSTQKADRRFRFPIFSSVRAGYIPPQPATADSYNYNNPNYNPYLAQSVLPPSAFTN 265
            :..:..|:|.:..|              ..|...|..:....|.|..|......||    .::..
  Rat   224 VSGSKCEIKVAQPK--------------EVYQQQQYGSGGRGNRNRGNRGSGGGQS----QSWNQ 270

  Fly   266 GWAHYVIPMAPKPTPGQNMAASLPSQQLAEHSLNGHGPDMWS-SYPKTGIYSAQEWTSSKVAEWG 329
            |:.:|           .|.....  ||       |:||.... .|...|.|.           :|
  Rat   271 GYGNY-----------WNQGYGY--QQ-------GYGPGYGGYDYSPYGYYG-----------YG 304

  Fly   330 PKAGHKHAQTSTN 342
            |  |:.::|.|||
  Rat   305 P--GYDYSQGSTN 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	30/77 (39%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	23/71 (32%)
Hnrnpab	XP_006246407.1	CBFNT	1..75	CDD:311868	8/24 (33%)
		RRM1_hnRNPAB	71..150	CDD:410151	31/80 (39%)
		RRM2_hnRNPAB	155..234	CDD:409997	26/99 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920