DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp4 and Hnrnpd

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_077380.2	Gene:	Hnrnpd / 79256	RGDID:	620365	Length:	353	Species:	Rattus norvegicus

Alignment Length:	328	Identity:	92/328 - (28%)
Similarity:	141/328 - (42%)	Gaps:	72/328 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 DGKTAIKEEGYEHLRKIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVD 82
            :..||.:||.     |:||||||..||.:.|:.:||:||.|.|..:..||::..|||||||.:.:
  Rat    86 EAATAQREEW-----KMFIGGLSWDTTKKDLKDYFSKFGDVVDCTLKLDPITGRSRGFGFVLFKE 145

  Fly    83 PKSVEIVQRARPHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYH 147
            .:||:.|...:.|.::.|:::.|.|   :..|....|                |:||:|||....
  Rat   146 SESVDKVMDQKEHKLNGKVIDPKRA---KAMKTKEPV----------------KKIFVGGLSPDT 191

  Fly   148 DENIVREYFSQFGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAPRKHWILQTLVEVK--- 209
            .|..:||||..||.|.|::|.||.:|.::|.|.|:.|.:....:|.:..:.|.:..:..|:|
  Rat   192 PEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAM 256

  Fly   210 -----RSTQKADRRFRFPIFSSVRAGYIPPQPATADSYNYNNPNYNPYLAQSVLPPSAFTNGWAH 269
                 :..|:...|..|...:..|.|. |.|.......||.|..|..|...|        .|:..
  Rat   257 SKEQYQQQQQWGSRGGFAGRARGRGGG-PSQNWNQGYSNYWNQGYGSYGYNS--------QGYGG 312

  Fly   270 YVIPMAPKPTPGQNMAASLPSQQLAEHSLNGHGPDMWSSYPKTGIYSAQEWTSSKVAEWGPKAGH 334
            |                            .|:....::||...|.||.|:....||:..|   ||
  Rat   313 Y----------------------------GGYDYTGYNSYYGYGDYSNQQSGYGKVSRRG---GH 346

  Fly   335 KHA 337
            :::
  Rat   347 QNS 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	32/76 (42%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	25/71 (35%)
Hnrnpd	NP_077380.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..89		0/2 (0%)
		CBFNT	<55..76	CDD:285369
		RRM1_hnRNPD_like	97..170	CDD:241019	30/72 (42%)
		RRM2_hnRNPD	181..255	CDD:241027	26/73 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910