DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp4 and Hnrnpa0

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_084148.1	Gene:	Hnrnpa0 / 77134	MGIID:	1924384	Length:	305	Species:	Mus musculus

Alignment Length:	186	Identity:	72/186 - (38%)
Similarity:	104/186 - (55%)	Gaps:	13/186 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LRKIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVDPKSVEIVQRARPH 95
            |.|:|||||:.||:...|||.|..||.:.|.||:.:|.:..||.||||||.:.:..:....|.||
Mouse     6 LCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPH 70

  Fly    96 TIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYHDENIVREYFSQFG 160
            .:|...||.|.|:.|:|..|.|....|             |::|:||||....|..:.|:|||||
Mouse    71 AVDGNTVELKRAVSREDSARPGAHAKV-------------KKLFVGGLKGDVAEGDLIEHFSQFG 122

  Fly   161 PVASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAPRKHWILQTLVEVKRSTQKAD 216
            .|...:::.|:::|::|.|||:.|....:|:||...:.|.|....||||::..|.|
Mouse   123 AVEKAEIIADKQSGKKRGFGFVYFQSHDAADKAAVVKFHPIQGHRVEVKKAVPKED 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	34/76 (45%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	27/71 (38%)
Hnrnpa0	NP_084148.1	RRM1_hnRNPA0	5..83	CDD:409764	34/76 (45%)
		RRM_SF	99..178	CDD:418427	30/78 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..211		1/1 (100%)
		HnRNPA1	253..>272	CDD:402981
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	265..305
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920