DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp4 and rbm19

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	XP_012825334.1	Gene:	rbm19 / 733862	XenbaseID:	XB-GENE-922190	Length:	920	Species:	Xenopus tropicalis

Alignment Length:	208	Identity:	55/208 - (26%)
Similarity:	89/208 - (42%)	Gaps:	43/208 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 DGKTAIKEEGYEHLRK----------IFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHS 72
            |.|..:||...|...:          :||..|:..|:.|||:..||:.|.|....:.:....:.|
Frog   671 DTKEEVKEMEVEDQEEDEEEALPGCTLFIKNLNFSTSEETLKEIFSKVGAVKSCSISKKKDKSGS 735

  Fly    73 ---RGFGFVTYVDPKSVE-IVQRARPHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFM 133
               .|||||.|..|:..: .:::.:..|:|...||.|.:      :|     ::..:...|....
Frog   736 LLPMGFGFVEYTKPEQAQKALRQLQKCTVDGHQVEIKLS------ER-----AIRAATSTERKKQ 789

  Fly   134 NSKR-----------IFLGGLKEYHDENIVREYFSQFGPVASVKLLMDRE-TGRQRAFGFLEFVD 186
            |||:           .|...::|      :||.||.||.:.:|:|..... ||..|.|||::||.
Frog   790 NSKKQQSSKILVRNVPFQATVRE------IRELFSTFGELKTVRLPKKMAGTGSHRGFGFVDFVT 848

  Fly   187 PSSAEKALAPRKH 199
            ...|::|.:...|
Frog   849 KQDAKRAFSALCH 861

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	24/90 (27%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	21/75 (28%)
rbm19	XP_012825334.1	RRM1_RBM19	2..77	CDD:241008
		RRM2_RMB19	279..350	CDD:240946
		RRM3_RBM19	384..462	CDD:241011
		RRM4_RBM19	570..641	CDD:241013
		RRM5_RBM19_like	695..774	CDD:240764	24/78 (31%)
		RRM6_RBM19	797..875	CDD:241015	21/71 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910