DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp4 and Hnrnpa1l2-ps2

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001159443.1	Gene:	Hnrnpa1l2-ps2 / 545091	MGIID:	3645633	Length:	320	Species:	Mus musculus

Alignment Length:	188	Identity:	75/188 - (39%)
Similarity:	114/188 - (60%)	Gaps:	13/188 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 EHLRKIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVDPKSVEIVQRAR 93
            |.|||:||||||.|||.::||..|.|:|.:.|.||:|||.:..|||||||||...:.|:....||
Mouse    11 EQLRKLFIGGLSFQTTDKSLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNAR 75

  Fly    94 PHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYHDENIVREYFSQ 158
            ||.:|.|:||.|.|:.|||.:|.|             ..:..|:||:||:||..:|:.:|:||.|
Mouse    76 PHKVDGKVVEPKRAISRQDSQRPG-------------AHLIVKKIFVGGIKEDTEEHHLRDYFEQ 127

  Fly   159 FGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAPRKHWILQTLVEVKRSTQKAD 216
            :|.:..::::.||.:|::|.|.|:.|.|..|.:..:..:.|.:.....||:::..|.:
Mouse   128 YGKIEVIEIMTDRGSGKKRDFAFVTFDDHDSVDTIVIQKYHNVNGHNCEVRKALSKQE 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	41/76 (54%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	23/71 (32%)
Hnrnpa1l2-ps2	NP_001159443.1	RRM_SF	12..92	CDD:302621	43/79 (54%)
		RRM_SF	105..181	CDD:302621	25/75 (33%)
		HnRNPA1	257..>281	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D560101at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010