DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp4 and msi1b

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001013534.1	Gene:	msi1b / 541389	ZFINID:	ZDB-GENE-050320-86	Length:	330	Species:	Danio rerio

Alignment Length:	335	Identity:	100/335 - (29%)
Similarity:	140/335 - (41%)	Gaps:	92/335 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVDPKSVEIVQRARPHTI 97
            |:||||||.|||.|.|:.:|.:||.|.:::|:||||:..||||||||:||...|:.|.....|.:
Zfish    21 KMFIGGLSWQTTQEGLKDYFCKFGEVKESMVMRDPVTKRSRGFGFVTFVDQAGVDKVLAQTRHEL 85

  Fly    98 DNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYHDENIVREYFSQFGPV 162
            |:|.::.|.|.||:      ....:|         ..:|:||:|||........|::||.|||.|
Zfish    86 DSKTIDPKVAFPRR------AQPKLV---------TRTKKIFVGGLSVNTTIEDVKQYFDQFGKV 135

  Fly   163 ASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAPRKHWILQTLVEVKRSTQK------ADRRFR- 220
            ....|:.|:.|.|.|.|||:.|.:....||......|.|...:||.|::..|      ...|.|
Zfish   136 DDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSSRGRA 200

  Fly   221 ------------------FPIF----------SSVRAGY---IPPQPATADSYNYNNPNYNP--- 251
                              :|.|          :|:..||   .|..|.||         |||
Zfish   201 RVMPYGMDAFMLGIGMLGYPGFQATTYAGRSYTSLTPGYTYQFPAIPLTA---------YNPMAA 256

  Fly   252 ------------------YLAQSVLPPSAFTNGWAH-------YVIPMAPKPTPGQNMAASLPSQ 291
                              :|..|...|.|...|.|:       |:...:|.|:.|  .:.||...
Zfish   257 AAAAAAVVRGSTPSRSAGFLGTSSPGPMADLYGTANQESAVSSYLSAASPAPSTG--FSHSLGGP 319

  Fly   292 QLAEHSLNGH 301
            .:|....||:
Zfish   320 LIATAFTNGY 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	38/76 (50%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	27/71 (38%)
msi1b	NP_001013534.1	RRM	<16..161	CDD:223796	63/154 (41%)
		RRM1_MSI1	20..96	CDD:241203	37/74 (50%)
		RRM2_MSI	110..183	CDD:240769	27/72 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910