DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp4 and hnrnpdl

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001011015.1	Gene:	hnrnpdl / 496424	XenbaseID:	XB-GENE-495016	Length:	297	Species:	Xenopus tropicalis

Alignment Length:	270	Identity:	74/270 - (27%)
Similarity:	114/270 - (42%)	Gaps:	60/270 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KEEGYEHLRKIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVDPKSVEI 88
            ::||     |:||||||..|:.:.|..:.|:||.|.|..:..|||:..|||||||.:.|..||:.
Frog    23 QDEG-----KMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAVSVDK 82

  Fly    89 VQRARPHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYHDENIVR 153
            |...:.|.:|.|:::.|.|...:                   |....|::|:|||.....|..::
Frog    83 VLETKEHKLDGKLIDPKRAKALK-------------------GKEPPKKVFVGGLSPETTEEQIK 128

  Fly   154 EYFSQFGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAPRKHWILQTLVEVK--------- 209
            :||..||.:.:::|.||.:|..:|.|.|:.:......:|.|..|.|.|.....|:|
Frog   129 QYFGGFGEIENIELPMDTKTNERRGFCFVTYTGEEPVKKLLESRFHQIGTGKCEIKVAQPKEVYR 193

  Fly   210 ---RSTQKADR-----------RFRFPIFSSVRAGYIPPQPATADSYNYNNPNYNPYLAQSVLPP 260
               :..||..|           |.|...::.   ||          .||.:.||..|........
Frog   194 QQQQKQQKGGRGAATGRGGARGRGRGQGWNQ---GY----------SNYYDQNYGSYGNNGSYAD 245

  Fly   261 SAFTNGWAHY 270
            ..:.|.::.|
Frog   246 QGYNNSYSGY 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	33/76 (43%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	22/71 (31%)
hnrnpdl	NP_001011015.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		RRM1_hnRPDL	27..102	CDD:410152	32/74 (43%)
		RRM2_hnRPDL	112..186	CDD:409998	23/73 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	192..224		5/31 (16%)
		Trnau1ap	222..>278	CDD:407550	9/47 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910