DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp4 and AgaP_AGAP002959

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	XP_001237407.3	Gene:	AgaP_AGAP002959 / 4577309	VectorBaseID:	AGAP002959	Length:	913	Species:	Anopheles gambiae

Alignment Length:	188	Identity:	46/188 - (24%)
Similarity:	81/188 - (43%)	Gaps:	31/188 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 DCKGDGKTAIKEEGYEHLRKIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFV 78
            |.:.|.|.     |.:..|::|:..||.:.|...:|..|....|  :::.|....|..|||||::
Mosquito   656 DSESDAKA-----GGDQSRQVFVSNLSFEVTETDIREIFPDLAI--ESIELVASSSGKSRGFGYM 713

  Fly    79 TYVD----PKSVEIVQR---ARPHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSK 136
            ....    ||::...:|   .||..|.| :...|...|.|              |...:.|..:|
Mosquito   714 QLASAEEVPKALSFDRRPLNGRPVFISN-VARDKTTRPHQ--------------FKYSSSFEPNK 763

  Fly   137 RIFLGGLKEYHDENIVREYFSQFGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKAL 194
             :|:.||.....:..:|..|..||.:..::::..| :|:.:...:||:...:||:.|:
Mosquito   764 -LFIKGLPFNLGQEELRRLFEPFGSIKDIRIVCFR-SGKSKGLAYLEYETETSAKNAV 819

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	22/83 (27%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	14/58 (24%)
AgaP_AGAP002959	XP_001237407.3	RRM_SF	671..740	CDD:302621	19/70 (27%)
		RRM_SF	760..840	CDD:302621	15/62 (24%)
		Lsm_interact	895..913	CDD:283133
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910