DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rbp4 and hnrnpa1b

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_956398.1	Gene:	hnrnpa1b / 378453	ZFINID:	ZDB-GENE-030912-14	Length:	422	Species:	Danio rerio

Alignment Length:	215	Identity:	79/215 - (36%)
Similarity:	121/215 - (56%)	Gaps:	26/215 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ACLGDCKGDGKTAI----KEEGY----EHLRKIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRD 66
            ||     |..:|.|    .:||.    |.|||:||||||.:||.::||..|.|:|.:.|.||::|
Zfish     8 AC-----GVARTEIVGRMSKEGQPREPEQLRKLFIGGLSFETTDDSLRAHFEQWGTLTDCVVMKD 67

  Fly    67 PVSNHSRGFGFVTYVDPKSVEIVQRARPHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAG 131
            |.:..|||||||||.....|.....||||.:|.::||.|.|:.|:|..:.....:|
Zfish    68 PNTKRSRGFGFVTYSSVDEVNASMDARPHKVDGRLVEPKRAVSREDSSKPFAHTTV--------- 123

  Fly   132 FMNSKRIFLGGLKEYHDENIVREYFSQFGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAP 196
                |:||:||:|:..:||.:|:||.|||.:..|::::|.:||.:|.|.|:.|.|..|.::.:..
Zfish   124 ----KKIFVGGIKDDTEENHLRDYFDQFGKIEVVEIMVDHKTGNKRGFAFVTFDDHDSVDRIVIQ 184

  Fly   197 RKHWILQTLVEVKRSTQKAD 216
            :.|.:.....||:::..|.:
Zfish   185 KYHTVNGHNCEVRKALSKQE 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	38/76 (50%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	25/71 (35%)
hnrnpa1b	NP_956398.1	RRM	<19..187	CDD:223796	70/180 (39%)
		RRM_SF	31..111	CDD:302621	40/79 (51%)
		RRM2_hnRNPA1	124..200	CDD:241024	27/75 (36%)
		HnRNPA1	367..>387	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BA81
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820