DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp4 and hnrnpa0b

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_999871.1	Gene:	hnrnpa0b / 334222	ZFINID:	ZDB-GENE-030131-6154	Length:	314	Species:	Danio rerio

Alignment Length:	188	Identity:	75/188 - (39%)
Similarity:	111/188 - (59%)	Gaps:	13/188 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 EHLRKIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVDPKSVEIVQRAR 93
            |.|.|:|:|||:.|||.:.||.:|.|||.:.|.||:::.....||.||||||...:..:....||
Zfish     5 EKLCKLFVGGLNVQTTNDGLRSYFEQFGNLTDCVVVQNDQLQRSRCFGFVTYSTSEEADAAMAAR 69

  Fly    94 PHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYHDENIVREYFSQ 158
            ||.:|.|.||.|.|:.|:|..|...:..|             |:||:||||:..:|..:.|:|||
Zfish    70 PHVVDGKNVEVKRAVAREDAGRPEALAKV-------------KKIFVGGLKDDIEEKDLTEFFSQ 121

  Fly   159 FGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAPRKHWILQTLVEVKRSTQKAD 216
            ||.:...:::.|::||::|.|||:.|.|..||:||:..:.|.|....||||::..|.:
Zfish   122 FGMIEKSEVITDKDTGKKRGFGFVHFEDNDSADKAVVLKFHMINGHKVEVKKALTKQE 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	35/76 (46%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	30/71 (42%)
hnrnpa0b	NP_999871.1	RRM1_hnRNPA0	6..84	CDD:240772	35/77 (45%)
		RRM_SF	100..179	CDD:302621	33/78 (42%)
		HnRNPA1	263..294	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920