DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rbp4 and hrpa-1

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001040945.1	Gene:	hrpa-1 / 177101	WormBaseID:	WBGene00001999	Length:	347	Species:	Caenorhabditis elegans

Alignment Length:	198	Identity:	70/198 - (35%)
Similarity:	119/198 - (60%)	Gaps:	16/198 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GDGKTAIKEEGYEHLRKIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYV 81
            |.|..:::.   |:|||||:|||::.||.:.:|.|:||||.:.|.:|:|||.:..||||||||:.
Worm    11 GSGDASLEP---ENLRKIFVGGLTSNTTDDLMREFYSQFGEITDIIVMRDPTTKRSRGFGFVTFS 72

  Fly    82 DPKSVEIVQRARPHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEY 146
            ....|:...:.|||.||.|.|:.|.|:||.|..|.            |:. :::||:::.|::|.
Worm    73 GKTEVDAAMKQRPHIIDGKTVDPKRAVPRDDKNRS------------ESN-VSTKRLYVSGVRED 124

  Fly   147 HDENIVREYFSQFGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAPRKHWILQTLVEVKRS 211
            |.|:::.|||:::|.|...::::|:.|.:.|.|||:.|.|..|.::.:..:.|.:.....:|::.
Worm   125 HTEDMLTEYFTKYGTVTKSEIILDKATQKPRGFGFVTFDDHDSVDQCVLQKSHMVNGHRCDVRKG 189

  Fly   212 TQK 214
            ..|
Worm   190 LSK 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	37/76 (49%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	20/71 (28%)
hrpa-1	NP_001040945.1	RRM1_hnRNPA_like	24..101	CDD:241022	37/76 (49%)
hrpa-1	NP_001040945.1	RRM2_hnRNPA_like	115..187	CDD:240774	20/71 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163585
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.850