Protein Alignment Rbp4 and tdp-1

DIOPT Version :10

• Sequence 1: NP_476935.1
• Gene: Rbp4 / 41668
• FlyBaseID: FBgn0010258
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_001254189.1
• Gene: tdp-1 / 174436
• WormBaseID: WBGene00006514
• Length: 414
• Species: Caenorhabditis elegans
• Alignment Length: 274
• Identity: 67/274 - (24%)
• Similarity: 96/274 - (35%)
• Gaps: 74/274 - (27%)

  Fly    34 IFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVDPKSVEIVQRARPHTID 98
            :.:.|:..:||.|..:.:|...|.|....:.|....| |:|||||..........|.....|.||
 Worm   175 LIVLGVDFKTTDECFQKYFEDIGTVVFCEIKRKSDGN-SKGFGFVRMSSVGEQNKVLAIPQHMID 238

  Fly    99 NKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYHDENIVREYFSQFGPVA 163
            .:         |.|.|...|     .|...:.|..:..|||:|.|.:..||:.:|:.   ||..|
 Worm   239 GR---------RCDVKVPDG-----RSLQDKQGRPSISRIFVGRLTDKVDEHQLRKV---FGDEA 286

  Fly   164 S--VKLLMDRETGRQRAFGFLEFVDPSSAEKA--------------------LAPRKH------- 199
            .  ::..:..:....:.|....||..||||.|                    ..||:.
 Worm   287 KSYIETAVVTDVFIPKPFRGFAFVTLSSAEAAERIVSKGSLTVNGLSVGLSIAQPREENNQSVGP 351

  Fly   200 -WILQTLVEVKRSTQKADRRFRFPIFSS-------VRAGYIPPQPATADSYNY---NNPNYNPYL 253
             :.|......:|...:.|||   ||.:.       ||    |||     .|:|   |:|....|.
 Worm   352 DYGLPAGYRNRRERDRPDRR---PIQNEAPLPMPFVR----PPQ-----DYSYRQQNSPLERRYW 404

  Fly   254 AQSVLPPSAFTNGW 267
            |    |..:...||
 Worm   405 A----PGDSRGPGW 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	34..105	CDD:473069	19/70 (27%)
		RRM2_hnRNPA_like	137..209	CDD:409766	22/101 (22%)
tdp-1	NP_001254189.1	TDP43_N	47..121	CDD:465833
		RRM_SF	174..247	CDD:473069	22/81 (27%)
		RRM_SF	262..339	CDD:473069	19/79 (24%)