DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rbp4 and Hnrnpa1

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001034218.1	Gene:	Hnrnpa1 / 15382	MGIID:	104820	Length:	373	Species:	Mus musculus

Alignment Length:	188	Identity:	74/188 - (39%)
Similarity:	115/188 - (61%)	Gaps:	13/188 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 EHLRKIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVDPKSVEIVQRAR 93
            |.|||:||||||.:||.|:||..|.|:|.:.|.||:|||.:..|||||||||...:.|:....||
Mouse    11 EQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNAR 75

  Fly    94 PHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYHDENIVREYFSQ 158
            ||.:|.::||.|.|:.|:|.:|.|             ..:..|:||:||:||..:|:.:|:||.|
Mouse    76 PHKVDGRVVEPKRAVSREDSQRPG-------------AHLTVKKIFVGGIKEDTEEHHLRDYFEQ 127

  Fly   159 FGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAPRKHWILQTLVEVKRSTQKAD 216
            :|.:..::::.||.:|::|.|.|:.|.|..|.:|.:..:.|.:.....||:::..|.:
Mouse   128 YGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQE 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	40/76 (53%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	24/71 (34%)
Hnrnpa1	NP_001034218.1	RRM1_hnRNPA1	12..92	CDD:241205	42/79 (53%)
		RRM2_hnRNPA1	105..181	CDD:241024	26/75 (35%)
		HnRNPA1	310..345	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BA81
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780