Protein Alignment Rbp4 and SF3B4

DIOPT Version :9

• Sequence 1: NP_476935.1
• Gene: Rbp4 / 41668
• FlyBaseID: FBgn0010258
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_005841.1
• Gene: SF3B4 / 10262
• HGNCID: 10771
• Length: 424
• Species: Homo sapiens
• Alignment Length: 360
• Identity: 75/360 - (20%)
• Similarity: 123/360 - (34%)
• Gaps: 106/360 - (29%)

  Fly    34 IFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVDPKSVEI---------- 88
            :::|||..:.:...|...|.|.|.|.:..:.:|.|:...:|:|||.::..:..:.
Human    15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMNMIKL 79

  Fly    89 ------VQRARPHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYH 147
                  |.:|..|   ||.::                   ||:           .||:|.|....
Human    80 YGKPIRVNKASAH---NKNLD-------------------VGA-----------NIFIGNLDPEI 111

  Fly   148 DENIVREYFSQFGPVASV-KLLMDRETGRQRAFGFLEFVDPSSAEKAL----------------- 194
            ||.::.:.||.||.:... |::.|.:||..:.:.|:.|....:::.|:
Human   112 DEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSY 176

  Fly   195 -------APRKHWILQTLVEVKRSTQKADRRFRF------------PIFSSVRAGYIPPQPATAD 240
                   ..|.....:.|:..:....:|||..:.            |:.||:.:|..||......
Human   177 AFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPG 241

  Fly   241 SYNYNNPNYNPYLAQSVLPPSAFTNGWAHYVIP--MAPKPTPGQNMAASLPSQQLAEHSLNGHGP 303
            |:           ...|.||.|...|     ||  |.|.|.|........||.........|||.
Human   242 SF-----------PPPVPPPGALPPG-----IPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGH 290

  Fly   304 DMWSSYPKTGIYSAQEWTSSKVAEWGPKA-GHKHA 337
            .....:|..|: .....:..::|..||.. ||.||
Human   291 SHPHPFPPGGM-PHPGMSQMQLAHHGPHGLGHPHA 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	19/91 (21%)
		RRM2_hnRNPA_like	137..209	CDD:240774	19/96 (20%)
SF3B4	NP_005841.1	RRM1_SF3B4	15..88	CDD:409771	15/72 (21%)
		RRM2_SF3B4	99..181	CDD:409772	18/92 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	207..424		32/135 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910