DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp4 and hnrnpa3

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	XP_031748359.1	Gene:	hnrnpa3 / 100144993	XenbaseID:	XB-GENE-5878765	Length:	385	Species:	Xenopus tropicalis

Alignment Length:	372	Identity:	104/372 - (27%)
Similarity:	158/372 - (42%)	Gaps:	91/372 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 EHLRKIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVDPKSVEIVQRAR 93
            |.|||:||||||.:||.::||..|.|:|.:.|.||:|||.:..|||||||||...:.|:....||
Frog    90 EQLRKLFIGGLSFETTDDSLREHFEQWGKLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMSAR 154

  Fly    94 PHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYHDENIVREYFSQ 158
            ||.:|.::||.|.|:.|:|..|.|             ..:..|:||:||:||..:|..:|:||..
Frog   155 PHKVDGRVVEPKRAVSREDSARPG-------------AHLTVKKIFVGGIKEDTEEYHLRDYFQS 206

  Fly   159 FGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAPRKHWILQTLVEVKRSTQKADRRFRFPI 223
            :|.:.:::::.||::|::|.|.|:.|.|..:.:|.:..:.|.|.....|||::..|.:.:    .
Frog   207 YGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQ----T 267

  Fly   224 FSSVRAGYIPPQPATADSYNY-NNPNYNPYLAQSVLPPSAFTNGWAHYVIPMAPKPTPGQNMAAS 287
            .|:.|.|            || ..|.|               .|..:...|.......|.....|
Frog   268 ASAQRGG------------NYGGGPGY---------------GGRGYGGSPGYGNQGGGYGGGGS 305

  Fly   288 LPSQQLAEHSLNGHGPDMWS--------SYPKTGIYSAQEWTSSKVAEWGPKAGHKHAQTSTNDR 344
                     ...|.|.|.::        :|...|.|..|:.::     :||..|...:..|:.
Frog   306 ---------GGGGGGYDGYNEGGNFGGGNYNDFGNYGGQQQSN-----YGPMKGGSFSGRSSG-- 354

  Fly   345 AKIDLKELQAATFNNKLDFGARGDADRMSGAGLGLGLTGGAAVGVGA 391
                                  |......|.|.|.|..||...|.|:
Frog   355 ----------------------GSGSGPYGGGYGSGGGGGGGGGGGS 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	39/76 (51%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	23/71 (32%)
hnrnpa3	XP_031748359.1	RRM1_hnRNPA_like	94..171	CDD:409992	39/76 (51%)
		RRM2_hnRNPA3	184..263	CDD:409996	26/78 (33%)
		HnRNPA1	328..>344	CDD:402981	5/20 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920