DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp4 and celf5

DIOPT Version :9

Sequence 1:	NP_476935.1	Gene:	Rbp4 / 41668	FlyBaseID:	FBgn0010258	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001090639.1	Gene:	celf5 / 100036604	XenbaseID:	XB-GENE-494002	Length:	486	Species:	Xenopus tropicalis

Alignment Length:	288	Identity:	65/288 - (22%)
Similarity:	103/288 - (35%)	Gaps:	74/288 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KIFIGGLSTQTTVETLRGFFSQFGIVADAVVLRDPVSNHSRGFGFVTYVDPKSVEIVQ------- 90
            |:|:|.:......:.|:..|.|||.:.:..||:|..:...:|..|:||....|....|
Frog    48 KLFVGQIPRNLEEKDLKPLFEQFGKIYELTVLKDRYTGMHKGCAFLTYCARDSAIKAQTALHEQK 112

  Fly    91 ----RARPHTIDNKIVETKHALPRQDFKRGGGVGSVVGSFGCEAGFMNSKRIFLGGLKEYHDENI 151
                .|||       ::.|   |.....|||                 .:::|:|.|.:...|..
Frog   113 TLPGMARP-------IQVK---PADSESRGG-----------------DRKLFVGMLSKQQSEEE 150

  Fly   152 VREYFSQFGPVASVKLLMDRETGRQRAFGFLEFVDPSSAEKALAPRKHWILQTL------VEVKR 210
            |...|..||.:....:|...: |..:...|::|...:.|:.|:.....  .||:      :.||.
Frog   151 VTSMFQAFGSIEECSVLRGPD-GSSKGCAFVKFSSHAEAQAAIQALHG--SQTMPGASSSLVVKF 212

  Fly   211 STQKADRRFR--------FPIFSSVRAGYIPPQPATADSYNYN-----NPNYNPYLAQSVLPPSA 262
            :....:|..|        ..||:...|..|.|..|.|.:....     :.::..||:.||..||.
Frog   213 ADTDKERTLRRMQQMVGQLGIFTPSLALPISPYSAYAQALMQQQTTVLSTSHGSYLSPSVAFPSC 277

  Fly   263 F--------TNGWAHYVIPMAP-KPTPG 281
            .        .||     :|.|| .|..|
Frog   278 HIQQIGAVNLNG-----LPAAPITPASG 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp4	NP_476935.1	RRM_SF	33..110	CDD:302621	21/87 (24%)
Rbp4	NP_476935.1	RRM2_hnRNPA_like	137..209	CDD:240774	16/77 (21%)
celf5	NP_001090639.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..39
		RRM1_CELF3_4_5_6	42..128	CDD:241076	22/89 (25%)
		PABP-1234	<49..374	CDD:130689	64/287 (22%)
		RRM2_CELF3_4_5_6	134..214	CDD:241079	18/82 (22%)
		RRM3_CELF3_4_5_6	397..475	CDD:241083
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910