DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqd and RIM4

DIOPT Version :9

Sequence 1:	NP_731825.1	Gene:	sqd / 41666	FlyBaseID:	FBgn0263396	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_011839.1	Gene:	RIM4 / 856361	SGDID:	S000001016	Length:	713	Species:	Saccharomyces cerevisiae

Alignment Length:	142	Identity:	44/142 - (30%)
Similarity:	66/142 - (46%)	Gaps:	13/142 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NKQVDTEINGEDFTKDVTADGPGSENG-DAGAAGSTNGSSDNQSAASGQRDDDRKLFVGGLSWET 67
            |.:.|:..||     ||..:..|..:| |:....:::|..|::...|....|.|.:|||.|..||
Yeast   298 NNREDSRRNG-----DVIEEECGHVHGSDSEEKLTSDGIYDDEDKDSEITIDKRSIFVGQLDKET 357

  Fly    68 TEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDKVSAADEHIINSKK---VDPK 129
            |.:||...|..:|:|:.||:...|    :..||||.:...||......::.|.|...|   |..|
Yeast   358 TREELNRRFSTHGKIQDINLIFKP----TNIFAFIKYETEEAAAAALESENHAIFLNKTMHVQYK 418

  Fly   130 KAKARHGKIFVG 141
            :...||.:.|.|
Yeast   419 EVGGRHNRKFSG 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqd	NP_731825.1	RRM_SF	58..129	CDD:302621	25/73 (34%)
sqd	NP_731825.1	RRM2_hnRNPD_like	137..211	CDD:240775	2/5 (40%)
RIM4	NP_011839.1	RRM	1..>191	CDD:223796
		RRM1_RIM4_like	91..176	CDD:409887
		RRM_SF	176..242	CDD:409669
		SF-CC1	300..>378	CDD:273721	27/82 (33%)
		RRM2_RIM4_like	343..420	CDD:409888	28/80 (35%)
		YppG	615..>669	CDD:372950
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960