DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqd and NPL3

DIOPT Version :9

Sequence 1:	NP_731825.1	Gene:	sqd / 41666	FlyBaseID:	FBgn0263396	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_010720.3	Gene:	NPL3 / 852042	SGDID:	S000002840	Length:	414	Species:	Saccharomyces cerevisiae

Alignment Length:	302	Identity:	98/302 - (32%)
Similarity:	135/302 - (44%)	Gaps:	69/302 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 KLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTE----AIDKV---S 114
            :|||.....:..|.||.:.||.:|.::.:.:        ..||||:.|...|    ||::|   |
Yeast   126 RLFVRPFPLDVQESELNEIFGPFGPMKEVKI--------LNGFAFVEFEEAESAAKAIEEVHGKS 182

  Fly   115 AADEHIINSKKVDPKKAKARHGKIFVGGLTTEISDEEIKTYFGQFGNIVEVEM------PFDKQK 173
            .|::.:    :|...|..|:..:|.:..|....|.:::|....:  |.:|...      .||
Yeast   183 FANQPL----EVVYSKLPAKRYRITMKNLPEGCSWQDLKDLARE--NSLETTFSSVNTRDFD--- 238

  Fly   174 SQRKGFCFITFDSEQVVTDLLKTPKQ-KIAGKEVDVKR-ATPKPENQM-------MGGMRGGPRG 229
                |...:.|.||:::.:.|:.... :..|..:.|:| ..|.|..:.       .||.|||.||
Yeast   239 ----GTGALEFPSEEILVEALERLNNIEFRGSVITVERDDNPPPIRRSNRGGFRGRGGFRGGFRG 299

  Fly   230 GMRGG--RGGYGG-RGGYNNQWDGQGSYGGYGGGYGGYGAGGYGDYYAGGY---YNGYDYGYDGY 288
            |.|||  |||:|| |||          :||..||||||..||||.|..|||   ..|||....||
Yeast   300 GFRGGFSRGGFGGPRGG----------FGGPRGGYGGYSRGGYGGYSRGGYGGSRGGYDSPRGGY 354

  Fly   289 -GYGGGFEGNGYGGGGG------GNMGGGRG---GPRGGGGP 320
             ...||:...||||...      |:.||.||   ||||..||
Yeast   355 DSPRGGYSRGGYGGPRNDYGPPRGSYGGSRGGYDGPRGDYGP 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqd	NP_731825.1	RRM_SF	58..129	CDD:302621	21/77 (27%)
sqd	NP_731825.1	RRM2_hnRNPD_like	137..211	CDD:240775	16/81 (20%)
NPL3	NP_010720.3	PHA03247	<11..87	CDD:223021
		RBD_RRM1_NPL3	126..192	CDD:409777	21/77 (27%)
		RRM2_SRSF1_4_like	200..271	CDD:409776	14/79 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910