DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqd and Hnrnpab

DIOPT Version :9

Sequence 1:	NP_731825.1	Gene:	sqd / 41666	FlyBaseID:	FBgn0263396	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	XP_006246407.1	Gene:	Hnrnpab / 83498	RGDID:	69255	Length:	332	Species:	Rattus norvegicus

Alignment Length:	330	Identity:	127/330 - (38%)
Similarity:	174/330 - (52%)	Gaps:	52/330 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 GSENGDAGA-AGSTNGSSDNQSAASGQRDDDRKLFVGGLSWETTEKELRDHFGKYGEIESINVKT 89
            ||..|...| :|:.||:..:|..||...:|..|:|||||||:|::|:|:|:|.|:||:....:|.
  Rat    44 GSGGGTTAAPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKM 108

  Fly    90 DPQTGRSRGFAFIVFTNTEAIDKVSAADEHIINSKKVDPKKAKARH----GKIFVGGLTTEISDE 150
            ||.|||||||.||:|.::.:::||....||.::.:.:|||||.|..    .|||||||..|.::|
  Rat   109 DPNTGRSRGFGFILFKDSSSVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEE 173

  Fly   151 EIKTYFGQFGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTPKQKIAGKEVDVKRATPKP 215
            :|:.||||||.|..:|:|.|.:.::|:||.||||..|..|..:|:.....::|.:.::|.|.||.
  Rat   174 KIREYFGQFGEIEAIELPIDPKLNKRRGFVFITFKEEDPVKKVLEKKFHTVSGSKCEIKVAQPKE 238

  Fly   216 ENQMMGGMRGGPRGGMRGGRGGYGGRG-----GYNNQWD-GQGSYGGYGGGYGGYGAGGYGDYYA 274
            ..|......||.....||.||..||:.     ||.|.|: |.|...|||.|||||....|| ||
  Rat   239 VYQQQQYGSGGRGNRNRGNRGSGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYG-YY- 301

  Fly   275 GGYYNGYDYGYDGYGYGGGFEGNGYGGGGGGNMGGGRGGPRGGGGPKGGGGFNGGKQRGGGGRQQ 339
             ||..||||..                                      |..|.||.:..||.|.
  Rat   302 -GYGPGYDYSQ--------------------------------------GSTNYGKSQRRGGHQN 327

  Fly   340 RHQPY 344
            .::||
  Rat   328 NYKPY 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqd	NP_731825.1	RRM_SF	58..129	CDD:302621	33/70 (47%)
sqd	NP_731825.1	RRM2_hnRNPD_like	137..211	CDD:240775	32/73 (44%)
Hnrnpab	XP_006246407.1	CBFNT	1..75	CDD:311868	11/30 (37%)
		RRM1_hnRNPAB	71..150	CDD:410151	37/78 (47%)
		RRM2_hnRNPAB	155..234	CDD:409997	32/78 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	84	1.000	Domainoid score	I8052
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3446
OMA	1	1.010	-	-		QHG45859
OrthoDB	1	1.010	-	-		D496221at33208
OrthoFinder	1	1.000	-	-		FOG0001417
OrthoInspector	1	1.000	-	-		otm46028
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR48033
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X985
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080