DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqd and hnrnpa3

DIOPT Version :9

Sequence 1:	NP_731825.1	Gene:	sqd / 41666	FlyBaseID:	FBgn0263396	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001315077.1	Gene:	hnrnpa3 / 751729	ZFINID:	ZDB-GENE-060224-1	Length:	340	Species:	Danio rerio

Alignment Length:	338	Identity:	129/338 - (38%)
Similarity:	175/338 - (51%)	Gaps:	43/338 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 QSAASGQRDDDRKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEA 109
            :|..|.:.:..||||:||||:||||..||.||.::|::....|..||...|||||.|:.:::...
Zfish     2 ESRDSKEPEQLRKLFIGGLSFETTEDSLRAHFEQWGKLTDCVVMRDPANKRSRGFGFVTYSSVSE 66

  Fly   110 IDKVSAADEHIINSKKVDPKKAKARHG-----------KIFVGGLTTEISDEEIKTYFGQFGNIV 163
            :|....|..|.::.:.|:||:|.:|..           ||||||:..:..:..|:.||..:|.|.
Zfish    67 VDAAMTARPHKVDGRVVEPKRAVSREDSNKPGAHLTVKKIFVGGIKEDTEEYHIREYFECYGKIE 131

  Fly   164 EVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTPKQKIAGKEVDVKRATPKPENQMMGGM--RGG 226
            .:::..::...:::||||:|||....|..::......|.....:|::|.||.|.|.....  |||
Zfish   132 TIDIMEERSTGKKRGFCFVTFDDHDTVDKIVAQKYHTINSHNCEVRKALPKQEMQSSSNQRYRGG 196

  Fly   227 PRGGMRG-----GRGGY-GGRG---GYNNQWDGQ--GSYGGYGGGYGGYGAG-GYGDYYAGGYYN 279
            ..|...|     ||||| ||||   |||. :.|.  |..||||||.||||.| |||:...||.:.
Zfish   197 GGGNFTGRGGNFGRGGYGGGRGGGDGYNG-FGGNYGGGPGGYGGGRGGYGGGPGYGNQGGGGGFG 260

  Fly   280 GYDYGYDGYGYGGGFEGNG--YGGGGGGNMG--GGRGGPR-----------GG--GGPKGGGGFN 327
            |:|...|...:||.|.|.|  .|||||||..  |..||.:           ||  .||.||||:.
Zfish   261 GFDNYNDRGNFGGNFGGGGGSSGGGGGGNYNDFGNYGGQQSNFGPMKGNNFGGRNSGPYGGGGYG 325

  Fly   328 GGKQRGGGGRQQR 340
            .|...||||...|
Zfish   326 SGGGGGGGGYGSR 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqd	NP_731825.1	RRM_SF	58..129	CDD:302621	28/70 (40%)
sqd	NP_731825.1	RRM2_hnRNPD_like	137..211	CDD:240775	21/73 (29%)
hnrnpa3	NP_001315077.1	RRM1_hnRNPA_like	14..91	CDD:241022	32/76 (42%)
		RRM2_hnRNPA3	104..183	CDD:241026	23/78 (29%)
		HnRNPA1	<296..>315	CDD:288479	4/18 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910