Protein Alignment sqd and SRSF1

DIOPT Version :10

• Sequence 1: NP_731825.1
• Gene: sqd / 41666
• FlyBaseID: FBgn0263396
• Length: 344
• Species: Drosophila melanogaster
• Sequence 2: NP_008855.1
• Gene: SRSF1 / 6426
• HGNCID: 10780
• Length: 248
• Species: Homo sapiens
• Alignment Length: 186
• Identity: 39/186 - (20%)
• Similarity: 58/186 - (31%)
• Gaps: 90/186 - (48%)

  Fly   137 KIFVGGLTTEISDEEIKTYFGQFGNIVEVEMPFDKQKSQRKG--FCFITFDSEQVVTDLLKTPKQ 199
            :|:||.|..:|..::|:..|.::|.|.::::     |::|.|  |.|:.|:..:...|.:
Human    17 RIYVGNLPPDIRTKDIEDVFYKYGAIRDIDL-----KNRRGGPPFAFVEFEDPRDAEDAV----- 71

  Fly   200 KIAGKEVDVKRATPKPENQMMGGMRGGPRGGMRGGRGGYGGRGGYNNQWDGQGSYGGYGGGYGGY 264
                                                                            |
Human    72 ----------------------------------------------------------------Y 72

  Fly   265 GAGGYGDYYAGGYYNGYDYGYDGYGYGGGFEGNGYGGGGGGNMGGGRGGPRGGGGP 320
            |..|              |.||||.....|..:|.|.|.||..|||.|.|||..||
Human    73 GRDG--------------YDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGP 114

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sqd	NP_731825.1	RRM1_hnRNPA_hnRNPD_like	58..129	CDD:409763
		RRM2_hnRNPD_like	137..211	CDD:240775	16/75 (21%)
SRSF1	NP_008855.1	RRM1_SRSF1	12..90	CDD:410010	25/160 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	88..134		15/27 (56%)
		RRM2_SRSF1	113..196	CDD:410160	2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	191..248
		Interaction with SAFB1	198..247