DRSC/TRiP Functional Genomics Resources

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Protein Alignment sqd and Hnrnpa2b1

DIOPT Version :9

Sequence 1:NP_731825.1 Gene:sqd / 41666 FlyBaseID:FBgn0263396 Length:344 Species:Drosophila melanogaster
Sequence 2:NP_001361674.1 Gene:Hnrnpa2b1 / 53379 MGIID:104819 Length:353 Species:Mus musculus


Alignment Length:334 Identity:121/334 - (36%)
Similarity:171/334 - (51%) Gaps:51/334 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 QRDDDRKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDKVSA 115
            :::..||||:||||:||||:.||:::.::|::....|..||.:.|||||.|:.|::...:|...|
Mouse    16 EKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMA 80

  Fly   116 ADEHIINSKKVDPKKAKARH-----------GKIFVGGLTTEISDEEIKTYFGQFGNIVEVEMPF 169
            |..|.|:.:.|:||:|.||.           .|:||||:..:..:..::.||.::|.|..:|:..
Mouse    81 ARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIIT 145

  Fly   170 DKQKSQRKGFCFITFDSEQVVTDLLKTPKQKIAGKEVDVKRATPKPENQMMGGMRGGPRGG---- 230
            |:|..:::||.|:|||....|..::......|.|...:|::|..:.|.|.:...|.| |||    
Mouse   146 DRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQSSRSG-RGGNFGF 209

  Fly   231 --MRGGRGGYGGRGGYNNQW--DGQGSYGGYGGGYGGYGAGGYGDYYAGGYYNGYDYGYDGYGYG 291
              .|||.|.:|...|.|.:.  ||.||..|:|.||.|||.|..|..:.|.  .||..|..|||.|
Mouse   210 GDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGS--PGYGGGRGGYGGG 272

  Fly   292 G---GFEGNGYGGG----GGGNMGGGR----------------------GGPRGGGGPKGGGGFN 327
            |   |.:|.|||||    ||||.|.|.                      ||.|..|||.|||.:.
Mouse   273 GPGYGNQGGGYGGGYDNYGGGNYGSGSYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYG 337

  Fly   328 GGKQRGGGG 336
            .|...|.||
Mouse   338 PGGSGGSGG 346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sqdNP_731825.1 RRM_SF 58..129 CDD:302621 29/70 (41%)
RRM2_hnRNPD_like 137..211 CDD:240775 22/73 (30%)
Hnrnpa2b1NP_001361674.1 Nuclear localization signal. /evidence=ECO:0000255 9..15
RRM1_hnRNPA2B1 19..99 CDD:410155 34/79 (43%)
RRM2_hnRNPA2B1 112..191 CDD:409995 23/78 (29%)
Disordered. /evidence=ECO:0000250|UniProtKB:P22626 193..353 61/157 (39%)
HnRNPA1 302..326 CDD:402981 2/23 (9%)
Nuclear targeting sequence. /evidence=ECO:0000250 308..347 13/39 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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