DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sqd and hnrnpdl

DIOPT Version :9

Sequence 1:	NP_731825.1	Gene:	sqd / 41666	FlyBaseID:	FBgn0263396	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001011015.1	Gene:	hnrnpdl / 496424	XenbaseID:	XB-GENE-495016	Length:	297	Species:	Xenopus tropicalis

Alignment Length:	326	Identity:	128/326 - (39%)
Similarity:	181/326 - (55%)	Gaps:	47/326 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 GAAGSTN-GSSDNQSAASGQRDDDRKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRS 96
            ||....| ||..|   ||..:.|:.|:|:|||||:|::|:|.::..::||:....:||||.||||
Frog     5 GATPDFNEGSKIN---ASKNQQDEGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRS 66

  Fly    97 RGFAFIVFTNTEAIDKVSAADEHIINSKKVDPKKAKARHG-----KIFVGGLTTEISDEEIKTYF 156
            |||.|::|.:..::|||....||.::.|.:|||:|||..|     |:|||||:.|.::|:||.||
Frog    67 RGFGFVLFKDAVSVDKVLETKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPETTEEQIKQYF 131

  Fly   157 GQFGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTPKQKIAGKEVDVKRATPK------P 215
            |.||.|..:|:|.|.:.::|:||||:|:..|:.|..||::...:|...:.::|.|.||      .
Frog   132 GGFGEIENIELPMDTKTNERRGFCFVTYTGEEPVKKLLESRFHQIGTGKCEIKVAQPKEVYRQQQ 196

  Fly   216 ENQMMGGMRGGP--RGGMRGGRGGYGGRGGYNNQWDGQGSYGGYGGGYGGYGAGGYGDYYAGGYY 278
            :.|..|| ||..  |||.||...|.|...||:|.:|  .:||.||.. |.|...||.:.|:|..|
Frog   197 QKQQKGG-RGAATGRGGARGRGRGQGWNQGYSNYYD--QNYGSYGNN-GSYADQGYNNSYSGYDY 257

  Fly   279 NGYDYGYDGYGYGGGFEGNGYGGGGGGNMGGGRGGPRGGGGPKGGGGFNGGKQRGGGGRQQRHQP 343
            :||:||  .|||..|:  ..|.|...                      ..||.||||..|..:||
Frog   258 SGYNYG--SYGYNQGY--TDYSGQQS----------------------TYGKARGGGNHQNNYQP 296

  Fly   344 Y 344
            |
Frog   297 Y 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqd	NP_731825.1	RRM_SF	58..129	CDD:302621	31/70 (44%)
sqd	NP_731825.1	RRM2_hnRNPD_like	137..211	CDD:240775	31/73 (42%)
hnrnpdl	NP_001011015.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21		8/18 (44%)
		RRM1_hnRPDL	27..102	CDD:410152	34/74 (46%)
		RRM2_hnRPDL	112..186	CDD:409998	31/73 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	192..224		12/32 (38%)
		Trnau1ap	222..>278	CDD:407550	25/62 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	85	1.000	Domainoid score	I8054
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45859
OrthoDB	1	1.010	-	-		D496221at33208
OrthoFinder	1	1.000	-	-		FOG0001417
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48033
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X985
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.030