Protein Alignment sqd and MSI1

DIOPT Version :10

• Sequence 1: NP_731825.1
• Gene: sqd / 41666
• FlyBaseID: FBgn0263396
• Length: 344
• Species: Drosophila melanogaster
• Sequence 2: NP_002433.1
• Gene: MSI1 / 4440
• HGNCID: 7330
• Length: 362
• Species: Homo sapiens
• Alignment Length: 222
• Identity: 86/222 - (38%)
• Similarity: 122/222 - (54%)
• Gaps: 14/222 - (6%)

  Fly    54 DDRKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDKVSAADE 118
            |..|:|:|||||:||::.||::||::||::...|..||.|.|||||.|:.|.:...:|||.|...
Human    18 DPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSR 82

  Fly   119 HIINSKKVDPK---------KAKARHGKIFVGGLTTEISDEEIKTYFGQFGNIVEVEMPFDKQKS 174
            |.::||.:|||         |...|..|||||||:...:.|::|.||.|||.:.:..:.|||..:
Human    83 HELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTN 147

  Fly   175 QRKGFCFITFDSEQVVTDLLKTPKQKIAGKEVDVKRATPKPENQMMGGMRGGPR---GGMRGGRG 236
            :.:||.|:||:||.:|..:.:....:|..|.|:.|:|.||......|..||..|   .||.....
Human   148 RHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFML 212

  Fly   237 GYG--GRGGYNNQWDGQGSYGGYGGGY 261
            |.|  |..|:........||.|...||
Human   213 GIGMLGYPGFQATTYASRSYTGLAPGY 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sqd	NP_731825.1	RRM1_hnRNPA_hnRNPD_like	58..129	CDD:409763	33/70 (47%)
		RRM2_hnRNPD_like	137..211	CDD:240775	29/73 (40%)
MSI1	NP_002433.1	RRM1_MSI	21..96	CDD:409990	36/74 (49%)
		PABP-1234	<32..339	CDD:130689	77/208 (37%)
		RRM2_MSI	110..183	CDD:240769	28/72 (39%)