DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqd and msi

DIOPT Version :9

Sequence 1:	NP_731825.1	Gene:	sqd / 41666	FlyBaseID:	FBgn0263396	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001247303.1	Gene:	msi / 43087	FlyBaseID:	FBgn0011666	Length:	634	Species:	Drosophila melanogaster

Alignment Length:	240	Identity:	86/240 - (35%)
Similarity:	124/240 - (51%)	Gaps:	28/240 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GPGSENGDAGAAGSTNGSSDNQ-----SAASGQRDDDRKLFVGGLSWETTEKELRDHFGKYGEIE 83
            |.|..||.|...||....|..:     |..||......|||||||||:|:..:|:::|..:|.:.
  Fly   166 GAGQNNGQAAMGGSNKSGSSGRSTPSLSGGSGSDPAPGKLFVGGLSWQTSSDKLKEYFNMFGTVT 230

  Fly    84 SINVKTDPQTGRSRGFAFIVFTNTEAIDKVSAADEHIINSKKVDPKKAKARH--------GKIFV 140
            .:.:..||.|.|||||.||.|.....::||.....|.::.||:|||.|..::        .||||
  Fly   231 DVLIMKDPVTQRSRGFGFITFQEPCTVEKVLKVPIHTLDGKKIDPKHATPKNRPRQANKTKKIFV 295

  Fly   141 GGLTTEISDEEIKTYFGQFGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTPKQKIAGKE 205
            ||::.:.|.||:|.||.|||.:.|..|..|:|..:.:||.|:||::|.||..:.:.....|..|:
  Fly   296 GGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQTKRHRGFGFVTFENEDVVDRVCEIHFHTIKNKK 360

  Fly   206 VDVKRATPKP---------ENQMMGGMRG-----GPRGGMRGGRG 236
            |:.|:|.||.         :.::|.|..|     .| |.:.|.||
  Fly   361 VECKKAQPKEAVTPAAQLLQKRIMLGTLGVQLPTAP-GQLIGARG 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqd	NP_731825.1	RRM_SF	58..129	CDD:302621	29/70 (41%)
sqd	NP_731825.1	RRM2_hnRNPD_like	137..211	CDD:240775	31/73 (42%)
msi	NP_001247303.1	RRM1_hnRNPA_hnRNPD_like	205..276	CDD:240771	29/70 (41%)
msi	NP_001247303.1	RRM2_MSI	292..365	CDD:240769	30/72 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463988
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4205
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D496221at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.750