Protein Alignment sqd and Hnrnpa1

DIOPT Version :10

• Sequence 1: NP_731825.1
• Gene: sqd / 41666
• FlyBaseID: FBgn0263396
• Length: 344
• Species: Drosophila melanogaster
• Sequence 2: NP_001386203.1
• Gene: Hnrnpa1 / 29578
• RGDID: 69234
• Length: 373
• Species: Rattus norvegicus
• Alignment Length: 372
• Identity: 127/372 - (34%)
• Similarity: 179/372 - (48%)
• Gaps: 78/372 - (20%)

  Fly    44 NQSAASGQRDDDRKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTE 108
            ::|.:..:.:..||||:||||:|||::.||.||.::|.:....|..||.|.|||||.|:.:...|
  Rat     2 SKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVE 66

  Fly   109 AIDKVSAADEHIINSKKVDPKKAKARHG-----------KIFVGGLTTEISDEEIKTYFGQFGNI 162
            .:|....|..|.::.:.|:||:|.:|..           ||||||:..:..:..::.||.|:|.|
  Rat    67 EVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKI 131

  Fly   163 VEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTPKQKIAGKEVDVKRATPKPE----------- 216
            ..:|:..|:...:::||.|:|||....|..::......:.|...:|::|..|.|
  Rat   132 EVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGR 196

  Fly   217 --NQMMGGMRGG--------PRGGMRGGRGGYGGR---GGYNNQWDG------QGSYG----GYG 258
              :...||.|||        .|||...||||:||.   |||....||      .|.||    ||.
  Rat   197 SGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGGPGYS 261

  Fly   259 GGYGGYGAG--GYGD----YYAGGYYNGYDYGYDGYGYGGGFEGNGYGGGG-------------- 303
            ||..|||:|  |||:    |...|.|:.|:.|..|.|:||| .|:.:||||
  Rat   262 GGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGGFGGG-SGSNFGGGGSYNDFGNYNNQSSN 325

  Fly   304 -----GGNMGGGRGGPRGGGG-----PKGGGGFNGGKQRG--GGGRQ 338
                 |||.||...||.||||     |:..||:.|.....  |.||:
  Rat   326 FGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRR 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sqd	NP_731825.1	RRM1_hnRNPA_hnRNPD_like	58..129	CDD:409763	29/70 (41%)
		RRM2_hnRNPD_like	137..211	CDD:240775	22/73 (30%)
Hnrnpa1	NP_001386203.1	RRM1_hnRNPA1	12..92	CDD:410154	34/79 (43%)
		RRM2_hnRNPA3	105..184	CDD:409996	23/78 (29%)
		HnRNPA1	313..345	CDD:463312	8/31 (26%)