Protein Alignment sqd and SRSF8

DIOPT Version :10

• Sequence 1: NP_731825.1
• Gene: sqd / 41666
• FlyBaseID: FBgn0263396
• Length: 344
• Species: Drosophila melanogaster
• Sequence 2: NP_115285.1
• Gene: SRSF8 / 10929
• HGNCID: 16988
• Length: 282
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 53/282 - (18%)
• Similarity: 79/282 - (28%)
• Gaps: 106/282 - (37%)

  Fly    58 LFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVF-TNTEAIDKVSAADEHII 121
            |.|..|::.|:...||..|.|||.:..:.:..:|.|...|||||:.| ...:|.|..:|.|
Human    16 LKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRDAQDAEAAMD---- 76

  Fly   122 NSKKVDPKKAKARHGKIFVGGLTTEISDEEIKTYFGQFGNIVEVEMPFDKQKSQRKGFCFITFDS 186
                                  ..|:...|::....::|
Human    77 ----------------------GAELDGRELRVQVARYG-------------------------- 93

  Fly   187 EQVVTDLLKTPKQKIAGKEVDVKRATPKPENQMMGGMRGGPRGGMRGGRGGYG------------ 239
                                  :|..|:       ..:|.|||..||  ||||
Human    94 ----------------------RRDLPR-------SRQGEPRGRSRG--GGYGRRSRSYGRRSRS 127

  Fly   240 --------GRGGYNNQWDGQGSYGGYGGGYGGYGAGGYG-DYYAGGYYNGYDYGYDGYGYGGGFE 295
                    .||...::...:..|.|.......|....|. ..|:...|:...|....|| |..:.
Human   128 PRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYG-GSHYS 191

  Fly   296 GNGYGGGGGGNMGGGRGGPRGG 317
            .:||...........|...:.|
Human   192 SSGYSNSRYSRYHSSRSHSKSG 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sqd	NP_731825.1	RRM1_hnRNPA_hnRNPD_like	58..129	CDD:409763	22/71 (31%)
		RRM2_hnRNPD_like	137..211	CDD:240775	3/73 (4%)
SRSF8	NP_115285.1	RRM_SRSF2_SRSF8	16..88	CDD:409751	24/97 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..282		29/181 (16%)