DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment side-IV and CG31773

DIOPT Version :9

Sequence 1:	NP_001034052.2	Gene:	side-IV / 41657	FlyBaseID:	FBgn0038156	Length:	1001	Species:	Drosophila melanogaster
Sequence 2:	NP_722953.1	Gene:	CG31773 / 326159	FlyBaseID:	FBgn0051773	Length:	758	Species:	Drosophila melanogaster

Alignment Length:	653	Identity:	118/653 - (18%)
Similarity:	203/653 - (31%)	Gaps:	270/653 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PTAPHPFPSP-----------------NVWRQLLLPLLMLSGISQVCSTYVEQDELM-QNLD--- 73
            |:.|.|...|                 |.: |:|.|   .||.:...|:..|||.:: |.|:
  Fly   257 PSTPQPAEKPEEKSPEHLAYLDAIKQLNSY-QVLEP---TSGRATTKSSRKEQDPVIEQTLECLE 317

  Fly    74 ---------RPVPLTTVQGVLGR-------QAMLPCD-------ISPQERDDAVYMVLWFREGDG 115
                     :.:|:..|.|..||       :::|.|.       .||.     :::.......||
  Fly   318 KSGLTKKDLKAIPVIQVAGSKGRGSTCAIVESILRCHGVKTGVLSSPH-----LFLTSERIRIDG 377

  Fly   116 EPIYNFDVRGRQFGQARLWSSPTAFG----TRAHFSSTT-------HPAQLKIDNIRIEDEGVYR 169
            ||:  .||   ||.:. .|...|...    |.::....|       |.|.:::..:.:.:.|.
  Fly   378 EPL--SDV---QFTEL-FWKINTDLANMQPTPSYNKIMTVMAFHAFHQAGVEVAILEVGNAGA-- 434

  Fly   170 CRVDFRNSPTRNLKINLTVIVPPDRPVIYGQNRHEKAGN-VESFSEGNDIVLS------------ 221
              .|..|..:....|.:|.:         |..:....|| :...:.....::.
  Fly   435 --SDATNIASHAQTIGITTL---------GWEQSSNLGNSLRDIAWAKASIMKPEANIYTNVTQT 488

  Fly   222 --CEVSGGRPR---------PNVTWYLDNTAIDE------SFEQRPDGKTINHLSY-------PN 262
              |||...:.:         |....|::....::      ::..|.:|.....|:|       |.
  Fly   489 ECCEVLAQKAKQIGAQLRRVPTFNDYVEGDMNNKLLMNKANYSMRLNGSLAVQLAYDFLKRHKPE 553

  Fly   263 --VGRQHLNSRLMCVASNTNLTPPNNRVVILDVNLKPIAVHILTKDRF----VSADRTYD--VEC 319
              ||.:|         ::|.|||..:|.:  ::..:|.....:..|.|    .||| |::  :.|
  Fly   554 YVVGLEH---------NSTLLTPGASRGI--EIFEQPGHFDFMRHDMFNVYLDSAD-TFESMMAC 606

  Fly   320 KSSGSKPPALITWW----KGSKQLKKLTKN----FNEPDNQSLSILTFTPGREDDGKYLTCRAEN 376
            :.          |:    :.::|.|.|..|    ||..|     :||.            .|:..
  Fly   607 RD----------WFYTRTRANRQPKILLFNKVNEFNAKD-----LLTI------------IRSNL 644

  Fly   377 QFIDGSAIEDKWRLIVHYQPTTTLKIGSSLNPDDIKEGDDAYFECIVLANPKPYKMSWFHNGKEL 441
            :|.:...:.                     ||:        |||..:||......|.| |..:||
  Fly   645 RFEEACFVP---------------------NPN--------YFEGEILAEEDGKAMVW-HGMEEL 679

  Fly   442 QHNISAGVILSDQSLVLQSVSRASAGDYTCLAVNSEGKGPSNPVTLRIRYAPICATDHEELLGAL 506
            |.                  ::.:||::..|. ...||..::.:::.|.
  Fly   680 QR------------------AKRNAGNWRALC-EENGKRDNSQLSISIN---------------- 709

  Fly   507 KHETLPLKCEVDSSPPADSFQWTFNSSGEQTELPARLHSSETGMSR---LNYTPSTDLDYGTISC 568
                             ..|::..|..|:|          :.||..   :..|.|..|...||||
  Fly   710 -----------------AFFEYLTNKYGKQ----------KYGMKNELDVLVTGSRQLVAATISC 747

  Fly   569 WAK 571
            ..|
  Fly   748 LRK 750

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
side-IV	NP_001034052.2	V-set	79..188	CDD:284989	26/133 (20%)
		IG_like	80..188	CDD:214653	26/132 (20%)
		Ig	210..281	CDD:299845	14/108 (13%)
		Ig	319..392	CDD:299845	13/80 (16%)
		IG_like	319..383	CDD:214653	13/71 (18%)
		IG_like	412..489	CDD:214653	16/76 (21%)
		IGc2	413..478	CDD:197706	14/64 (22%)
		Ig_3	509..572	CDD:290638	14/66 (21%)
		fn3	593..675	CDD:278470
CG31773	NP_722953.1	folC	309..745	CDD:273659	99/590 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3515
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900