Protein Alignment side-IV and Btn1a1

DIOPT Version :10

• Sequence 1: NP_001034052.2
• Gene: side-IV / 41657
• FlyBaseID: FBgn0038156
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: NP_001163808.1
• Gene: Btn1a1 / 306956
• RGDID: 1306984
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 574
• Identity: 120/574 - (20%)
• Similarity: 191/574 - (33%)
• Gaps: 180/574 - (31%)

  Fly    77 PLTTVQGVLGRQAMLPCDISPQERDDAVYMVLWFR--------------EGDGEPIYNFDVRGRQ 127
            |..:|..|:|..|.|.|..||....:.:.: ||||              |.:||.:..:
  Rat    35 PQESVLAVVGSDAELTCRFSPNASSEQMEL-LWFRQTRSPAVLLYRAGQEQEGEQMTEY------ 92

  Fly   128 FGQARLWSSPTAFGTRAHFSSTTHPAQLKIDNIRIEDEGVYRCRVDFRNSPTRNLKINLTVIVPP 192
            .|:|.|.::....|.          |.|:|..:|:.|:|.|||.:. .|..:....::|.|....
  Rat    93 HGRATLVTARLLDGL----------ATLRIRGVRVSDQGQYRCFLK-DNDDSEEAAVHLKVAAVG 146

  Fly   193 DRPVIYGQNRHEKAGNVESFSEGNDIVLSCEVSGGRPRPNVTWYLDNTAI--DESFEQRPDGKTI 255
            ..|.|           .....|..|:.|.|..||..|.|.|.|...|..:  ..|..:.||.:.:
  Rat   147 SDPYI-----------SMKVQENGDMELECTSSGWYPEPQVQWRTANREMLPPTSESRNPDTEGL 200

  Fly   256 NHLSYPNVGRQHLNSRLMCVASN------------------TNLTP--PNNRVVILDVNLKPIAV 300
            ..::...:.|.:....:.|...|                  ..|||  ....:|||.:....|..
  Rat   201 FTVTASMMIRDNSIKNMSCCIQNILLGQGKEVEISLPAPFLPRLTPWIVALAIVILALGFLAIGS 265

  Fly   301 HILT-----------KDRFVSADRTY-DVECKSSG-----------SKPPALITWWKGSKQLKKL 342
            ...|           |..|.|.:|.. ::.||.:.           :..|.|.. ::.||.::..
  Rat   266 IFFTWKLYKERSRERKKEFGSKERLLEELRCKKTALHEVDVTLDPDTAHPHLFL-YEDSKSVRLE 329

  Fly   343 TKNFNEPDNQS--------LSILTFTPGR---------EDDGKYLTCRAENQFIDGSAIEDKWRL 390
            ......||...        |...|||.||         ..|.....|| ||....|
  Rat   330 DSRQILPDRPERFDSWPCVLGRETFTSGRHYWEVEVGDRTDWAIGVCR-ENVVKKG--------- 384

  Fly   391 IVHYQPTTTLKIGSSLNPDD----IKEGDDAYFECIVLANP-----KPYKMSWFHNGKELQHNIS 446
               :.|.|         ||:    ::...:.|:....|..|     .|.::..|     |.:.:
  Rat   385 ---FDPMT---------PDNGFWAVELYGNGYWALTPLRTPLRLAGPPRRVGVF-----LDYEL- 431

  Fly   447 AGVI----LSDQSLVLQSVSRASAG---DYTCLAVNSEGKGPSNPVTLRIRYAPICATDHEELLG 504
             |.|    :||.||:....|.:.:|   .:.||.  |.||   .|:|:    .|......:..:.
  Rat   432 -GDISFYNMSDGSLIYAFPSISFSGPLRPFFCLW--SCGK---KPLTI----CPTANVPEKITVI 486

  Fly   505 ALKHETLPLKCEVDSSPPADSFQWTFNSSGEQTELPARLHSSETGMSRLNYTPS 558
            |...:.:||      ||..:.     ::||::..|.::|         :.::||
  Rat   487 ANVQDNIPL------SPLGEG-----STSGDKDSLHSKL---------IPFSPS 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
side-IV	NP_001034052.2	V-set	79..188	CDD:462230	30/122 (25%)
		Ig	210..281	CDD:472250	17/90 (19%)
		Ig strand B	218..222	CDD:409353	1/3 (33%)
		Ig strand C	232..236	CDD:409353	1/3 (33%)
		Ig	<317..392	CDD:472250	20/102 (20%)
		Ig strand C	329..333	CDD:409353	1/3 (33%)
		Ig strand E	355..359	CDD:409353	0/3 (0%)
		Ig strand F	369..374	CDD:409353	1/4 (25%)
		Ig strand G	385..388	CDD:409353	0/2 (0%)
		Ig	411..479	CDD:472250	17/79 (22%)
		Ig strand B	417..421	CDD:409353	1/3 (33%)
		Ig strand C	431..435	CDD:409353	0/3 (0%)
		Ig strand E	454..458	CDD:409353	2/3 (67%)
		Ig strand F	468..473	CDD:409353	1/4 (25%)
		Ig	494..576	CDD:472250	11/65 (17%)
		Ig strand B	511..515	CDD:409353	2/3 (67%)
		Ig strand C	525..529	CDD:409353	0/3 (0%)
		Ig strand E	551..555	CDD:409353	0/3 (0%)
		Ig strand F	566..570	CDD:409353
		fn3	593..675	CDD:394996
Btn1a1	NP_001163808.1	Ig	30..143	CDD:472250	31/125 (25%)
		Ig strand B	47..51	CDD:409353	2/3 (67%)
		Ig strand C	63..67	CDD:409353	1/4 (25%)
		Ig strand E	108..112	CDD:409353	2/3 (67%)
		Ig strand F	122..127	CDD:409353	3/4 (75%)
		Ig strand G	135..138	CDD:409353	0/2 (0%)
		Ig	153..223	CDD:472250	16/69 (23%)
		Ig strand B	161..165	CDD:409353	1/3 (33%)
		Ig strand C	175..179	CDD:409353	1/3 (33%)
		Ig strand E	205..209	CDD:409353	0/3 (0%)
		Ig strand F	216..221	CDD:409353	1/4 (25%)
		SPRY_PRY_BTN1_2	304..474	CDD:293991	43/208 (21%)