Protein Alignment side-IV and LOC1281286

DIOPT Version :10

• Sequence 1: NP_001034052.2
• Gene: side-IV / 41657
• FlyBaseID: FBgn0038156
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: XP_061499040.1
• Gene: LOC1281286 / 1281286
• VectorBaseID: AGAMI1_012297
• Length: 984
• Species: Anopheles gambiae
• Alignment Length: 1045
• Identity: 346/1045 - (33%)
• Similarity: 508/1045 - (48%)
• Gaps: 159/1045 - (15%)

  Fly    44 QLLLPLLMLSGISQV---CSTYVEQDELMQNLDRPVPLTTVQGVLGRQAMLPCDISPQERDDAVY 105
            :|:|.|||:.|....   |..:        ..|.|..|..|  ::...|.:.||:|....:|.:.
Mosquito    12 RLMLLLLMVGGGKWALVNCEGF--------KADVPTHLEKV--LVNETAQIKCDVSSNLTNDRIL 66

  Fly   106 MVLWFREGDGEPIYNFDVRGRQFGQARLWSSPTAFGTRAHFSSTTHP--AQLKIDNIRIEDEGVY 168
            :|:|::  |..|||::|.||........|........||:|.:|...  |.|.|..::.:|.|::
Mosquito    67 LVVWYK--DNVPIYSYDTRGPHVNSPSHWKDVAILEDRANFKTTREQSRAVLVISPVQKKDAGIF 129

  Fly   169 RCRVDFRNSPTRNLKINLTVIVPPDRPVIYGQNRHEKAG-----NVESFSEGNDIVLSCEVSGGR 228
            ||||||..|||:|..:||.::||||.|.|     |.:||     :...:.||.|:||.|.|:||.
Mosquito   130 RCRVDFLLSPTKNSNVNLEIVVPPDVPKI-----HNEAGVVLPSHAGPYEEGGDLVLICVVTGGN 189

  Fly   229 PRPNVTW-----YLDNTAIDESFEQRPDGKTINHLSYPNVGRQHLNSRLMCVASN---TNLTPPN 285
            |.|.:||     .|.:..||.:.|.....:    |...|:.|.|.::...|.|||   .|:|..
Mosquito   190 PTPKITWSSNGKTLPSAMIDYAHESTLSSR----LVVRNLSRAHQHNVYSCQASNFYRRNVTAN- 249

  Fly   286 NRVVILDVNLKPIAVHILTKDRFVSADRTYDVECKSSGSKPPALITWWKGSKQLKKLTKNFNEPD 350
               |.:::.|:|:||.|:.....:||||.|.|:|:|.||:|||.||||.|..||....:..:|..
Mosquito   250 ---VTIELRLRPLAVEIVNGSSPLSADRRYIVQCQSVGSRPPAKITWWMGGVQLTATNQTTSEDG 311

  Fly   351 NQSLSILTFTPGREDDGKYLTCRAENQFIDGSAIEDKWRLIVHYQPTTTLKIGSSLNPDDIKEGD 415
            |.:|:.|:|||.|||.||.|.|||.|:.:.....|...:|.|.|.||..|::|.::||:||:|||
Mosquito   312 NSTLASLSFTPTREDHGKTLICRATNELVKRGTKETSMKLNVFYLPTLKLELGINMNPEDIEEGD 376

  Fly   416 DAYFECIVLANPKPYKMSWFHNGKELQHNISAGVILSDQSLVLQSVSRASAGDYTCLAVNSEGKG 480
            |.||||.|.|||..||:.|.||.|.:|||..:|||:|..:|.||:|:|..||:|||:|.|.||.|
Mosquito   377 DVYFECKVNANPSAYKVVWKHNDKVVQHNSKSGVIMSSTALALQTVTRHQAGNYTCIASNVEGDG 441

  Fly   481 PSNPVTLRIRYAPICATDHEELLGALKHETLPLKCEVDSSPPADSFQWTFNSSGEQTELPA---R 542
            .||.|.|::.|.|||..|.:::.|..::|...:.|:||:.||.:||:|:||::.|..::|.   |
Mosquito   442 ESNTVDLKVMYKPICRPDQKKIYGVARNEAAEILCQVDAYPPPESFKWSFNNTAETIDMPQSGYR 506

  Fly   543 LHSSETGMSRLNYTPSTDLDYGTISCWAKNSIGTQKSPCVFQIVAAGRPFPLQNCSVTNQSVDSL 607
            :|:.:.  |.|.|||..:||||||.|||.|.:|.||.||||.::|||:|....|||:.||:.:||
Mosquito   507 VHAEQA--SSLTYTPVKELDYGTIMCWADNVVGQQKEPCVFHLIAAGKPEMPYNCSLVNQTSESL 569

  Fly   608 QVDCLEGFDGGLPQGFMLELVELNTLRLARNITVSHTPVTFVIDNLDQAATYRMVIFAVNAKGRS 672
            :|||.||||||..|.|::|:.:|.:..|..|:: |..|: |.::.||.....::||:|.|.:|||
Mosquito   570 EVDCAEGFDGGQRQWFVMEIYDLQSHALLANVS-SKLPI-FTVNGLDAGLLLKIVIYATNMRGRS 632

  Fly   673 EPTIIDDINFKGVAKFTGASTGLSMPLSPFLAGLTLFCGLLFAIFCIML---AAIYRRISNRRSD 734
            ||.::.....|...|.||...  ...|:| :..:.:|.|:|..:.||::   ||...|.:..:..
Mosquito   633 EPILLQAYTLKAAEKQTGPHA--EFELTP-IVSIGIFIGILTVLICIIIAVAAAFKLRATQAKQH 694

  Fly   735 S-------------NLKVAKHTQLTI-PADCQLDPLHPGVQTDGSGNHQPHHSLLPLNCDG---R 782
            :             ||.:.:...|.: .::...|..:|.|.   ..|..|.:.|:..|...   .
Mosquito   695 TTATTTTAGGKRPGNLPIKEKISLPLSQSEDMYDEKNPDVV---PSNEDPDYKLISANQTPTALH 756

  Fly   783 NAVDCGALGDVGGGGVGVGLDGGIKGSSPIGLVAMPGDTLRSNARNRH-SPMADQADIDDTDPDV 846
            |:: |.:..|:.|..:   ||...|            ..|..:|...| :.:|.....|||....
Mosquito   757 NSL-CNSKHDIIGRTI---LDDSRK------------TYLTGSASEVHYAELALAIPHDDTGGKT 805

  Fly   847 IPNQYEKRPLKSLVSPPGFASPSNRLMQRDYLRE---------------------TELTKGGSDV 890
            ..|.:    |..|..||.:          :|..|                     |:...|.:..
Mosquito   806 HLNNH----LNKLPPPPAY----------NYFDEPTIYAQIDHGGSFGKGVPPPPTQSHPGSTIA 856

  Fly   891 GMGAAEGLSSIGLMSSSGNEVLHYTFR---------------PSKQISYA-----TLNKKGITTC 935
            |:|:. |.||..|:|....:..|:...               |.....:|     |.....:...
Mosquito   857 GVGST-GSSSFPLISPVSQQQQHHHHHHPLTLQLQQDATQPAPPHNQHHAPHTPHTPTTASLLQL 920

  Fly   936 SPPLGSLNYSVSTSTPTSSYHLTPQPMEVSLLSPNNPSVTSSLSEYRFRTGPEIVTTSNRI---- 996
            |.|||....:|...:|....|..||....||.|.|.....|  .:|.    .||||....:
Mosquito   921 SQPLGQHPGAVLAHSPLQLSHALPQSPSASLPSANGGGGGS--KQYL----REIVTVRTPLAFSQ 979

  Fly   997 QESCI 1001
            ||||:
Mosquito   980 QESCV 984

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
side-IV	NP_001034052.2	V-set	79..188	CDD:462230	37/110 (34%)
		Ig	210..281	CDD:472250	25/78 (32%)
		Ig strand B	218..222	CDD:409353	2/3 (67%)
		Ig strand C	232..236	CDD:409353	2/8 (25%)
		Ig	<317..392	CDD:472250	34/74 (46%)
		Ig strand C	329..333	CDD:409353	2/3 (67%)
		Ig strand E	355..359	CDD:409353	1/3 (33%)
		Ig strand F	369..374	CDD:409353	2/4 (50%)
		Ig strand G	385..388	CDD:409353	1/2 (50%)
		Ig	411..479	CDD:472250	39/67 (58%)
		Ig strand B	417..421	CDD:409353	2/3 (67%)
		Ig strand C	431..435	CDD:409353	1/3 (33%)
		Ig strand E	454..458	CDD:409353	1/3 (33%)
		Ig strand F	468..473	CDD:409353	3/4 (75%)
		Ig	494..576	CDD:472250	34/84 (40%)
		Ig strand B	511..515	CDD:409353	0/3 (0%)
		Ig strand C	525..529	CDD:409353	2/3 (67%)
		Ig strand E	551..555	CDD:409353	2/3 (67%)
		Ig strand F	566..570	CDD:409353	2/3 (67%)
		fn3	593..675	CDD:394996	35/81 (43%)
LOC1281286	XP_061499040.1	None