DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment side-IV and si:ch211-66e2.5

DIOPT Version :9

Sequence 1:	NP_001034052.2	Gene:	side-IV / 41657	FlyBaseID:	FBgn0038156	Length:	1001	Species:	Drosophila melanogaster
Sequence 2:	XP_001920347.3	Gene:	si:ch211-66e2.5 / 100150500	ZFINID:	ZDB-GENE-131121-180	Length:	302	Species:	Danio rerio

Alignment Length:	285	Identity:	69/285 - (24%)
Similarity:	107/285 - (37%)	Gaps:	52/285 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 GNDIVLSCEVSGGRPRPNVTW----YLDNTAIDESFEQRPDGKTINHLSYPNVGRQHLNSRLMCV 275
            |:.:.:||..|  ||...:.|    ...:|..|.|.:.|.|..| :.:..|             :
Zfish    36 GDPVTVSCVAS--RPVRVLGWESIIAASHTQHDLSVQWRVDSLT-DWIEEP-------------I 84

  Fly   276 ASNTNLTPPNNRVVILDVNL--KP--IAVHILTKDRFVSADRTYDVECKSSGSKPP--ALITWWK 334
            ......|.|......|::.|  ||  :::.::.....|...|.|.::|:.....|.  .::.|::
Zfish    85 CYGVFFTAPRQCEEKLNLVLYKKPDSVSISLVNHSSPVVEGREYQLQCEVHNVAPVQYLVLRWYR 149

  Fly   335 GSKQLKKLTKNFNE--PDN--QSLSILTFTPGREDDGKYLTCRAENQF-IDG-----SAIEDKWR 389
              :|.:....:|:|  |..  |..|.|...|.|.:||....|.||.|. .:|     :.:.....
Zfish   150 --EQTEVYNHSFSELTPATPVQVSSTLLIVPNRAEDGAQYRCEAELQLGPEGPQPPPTVLSPSLN 212

  Fly   390 LIVHYQPTTTLKIGSSLNPDDIKEGDDAYFECIVLANPKPYKMSWFHNGKELQHNISAGVILSDQ 454
            :.|||.|.........|   ::.||.:...:|....||.|..: |  ....||.......:|.|.
Zfish   213 IAVHYPPDFRSPKEEQL---EVSEGSEVVLDCTAEGNPLPVYI-W--TSPNLQEKADDQPVLKDA 271

  Fly   455 SLVLQSVSRASAGDYTCLAVNSEGK 479
            ||        |.|.|||.|.|..||
Zfish   272 SL--------SPGVYTCTASNILGK 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
side-IV	NP_001034052.2	V-set	79..188	CDD:284989
		IG_like	80..188	CDD:214653
		Ig	210..281	CDD:299845	14/69 (20%)
		Ig	319..392	CDD:299845	19/84 (23%)
		IG_like	319..383	CDD:214653	19/75 (25%)
		IG_like	412..489	CDD:214653	22/68 (32%)
		IGc2	413..478	CDD:197706	20/64 (31%)
		Ig_3	509..572	CDD:290638
		fn3	593..675	CDD:278470
si:ch211-66e2.5	XP_001920347.3	Ig	108..203	CDD:299845	23/96 (24%)
		IG_like	122..196	CDD:214653	21/75 (28%)
		IG_like	227..293	CDD:214653	23/76 (30%)
		Ig_2	227..284	CDD:290606	20/70 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910