DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment side-IV and si:ch211-66e2.3

DIOPT Version :9

Sequence 1:	NP_001034052.2	Gene:	side-IV / 41657	FlyBaseID:	FBgn0038156	Length:	1001	Species:	Drosophila melanogaster
Sequence 2:	NP_001108576.1	Gene:	si:ch211-66e2.3 / 100141487	ZFINID:	ZDB-GENE-080226-7	Length:	315	Species:	Danio rerio

Alignment Length:	296	Identity:	73/296 - (24%)
Similarity:	112/296 - (37%)	Gaps:	75/296 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 GNDIVLSCEVS------------GGRPRPN---VTWYLDNTAIDESFEQRPDGKTINHLSYPNVG 264
            |:.:.::|..|            ||.|...   :||.:....   .:|.:|.      ..|.|.|
Zfish    38 GDPVSVNCSTSVTHMGMGWESTVGGVPLSTASLITWRVSELT---DWEIQPP------FCYINYG 93

  Fly   265 RQHLNSRLMCVASNTNLTPPNNRVVILDVNL--KPIAVHILTKDRFVSADRTYDVECKSSGSKPP 327
            :|       |             .|.|.|.:  .|.:|.|.|.::.:.....|:::|......|.
Zfish    94 KQ-------C-------------EVALPVTVYKTPDSVSISTVNQTMIEGNQYELQCDVYNVAPV 138

  Fly   328 ALIT--WWKGSKQLKK--LTKNFNEPDNQSLSILTFTPGREDDGKYLTCRAE-NQFIDG-----S 382
            ..:|  |:||...:.:  .|.....|.|:: |.|...|.|.|||..:.|..| |...:|     :
Zfish   139 QKLTVNWYKGETLVDQTSFTDTIKSPVNKT-SKLLIRPDRADDGAQIRCEVELNLGEEGPQPPPT 202

  Fly   383 AIEDKWRLIVHYQPTTTLKIGSSLNPDDIKEGDDAYFECIVLANPKPYKMSWFHNGKELQHNISA 447
            ...:..|:.|:|:|.      .|.:.:.|...:|....|.|.|||... .||  :.:.|...||:
Zfish   203 NTSEPLRITVYYKPK------HSNSTEIISWSNDVSLNCTVKANPAAV-YSW--HSEHLTEKISS 258

  Fly   448 GVILSDQSLVLQSVSRASAGDYTCLAVNSEGKGPSN 483
            .||.|         |..|.|:|||:|.|..|:...|
Zfish   259 SVIQS---------STLSPGNYTCIATNFLGEDKKN 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
side-IV	NP_001034052.2	V-set	79..188	CDD:284989
		IG_like	80..188	CDD:214653
		Ig	210..281	CDD:299845	15/80 (19%)
		Ig	319..392	CDD:299845	21/82 (26%)
		IG_like	319..383	CDD:214653	20/73 (27%)
		IG_like	412..489	CDD:214653	24/72 (33%)
		IGc2	413..478	CDD:197706	22/64 (34%)
		Ig_3	509..572	CDD:290638
		fn3	593..675	CDD:278470
si:ch211-66e2.3	NP_001108576.1	Ig	108..208	CDD:299845	25/100 (25%)
		Ig_3	215..277	CDD:290638	24/79 (30%)
		IG_like	230..288	CDD:214653	24/68 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910