Protein Alignment side-IV and SIGLEC14

DIOPT Version :9

• Sequence 1: NP_001034052.2
• Gene: side-IV / 41657
• FlyBaseID: FBgn0038156
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: NP_001092082.1
• Gene: SIGLEC14 / 100049587
• HGNCID: 32926
• Length: 396
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 107/492 - (21%)
• Similarity: 160/492 - (32%)
• Gaps: 180/492 - (36%)

  Fly    45 LLLPLLMLSGISQVCSTYVEQDELMQNLDRPVPLTTVQGVLGRQAMLPCDISPQER----DDAVY 105
            ||||||....:         |::.:..|.....:|..:|:.   .::||..|...|    ...:|
Human     5 LLLPLLWGGSL---------QEKPVYELQVQKSVTVQEGLC---VLVPCSFSYPWRSWYSSPPLY 57

  Fly   106 MVLWFREGDGEPIY-------NFDVRGRQFGQARLWSSPTAFGTRAHFSSTTHPAQLKIDNIRIE 163
             |.|||:|: .|.|       |.|.|.:...|.|.         |...........|.|.:.|:|
Human    58 -VYWFRDGE-IPYYAEVVATNNPDRRVKPETQGRF---------RLLGDVQKKNCSLSIGDARME 111

  Fly   164 DEGVYRCRV----DFRNSPTRNLKINLTVIVPPDRPVIYGQNRHEKAGNVESFSEGNDIVLSCEV 224
            |.|.|..||    |.:.|..:| |:||.|....::|.|:         .:|....|....|||.:
Human   112 DTGSYFFRVERGRDVKYSYQQN-KLNLEVTALIEKPDIH---------FLEPLESGRPTRLSCSL 166

  Fly   225 SGGRPRPNVTWYLDNTAIDESFEQRPDGKTINHLSYPNVGRQHLNSRLMCVASNTNLTPPNNRVV 289
            .|
Human   167 PG--------------------------------------------------------------- 168

  Fly   290 ILDVNLKPIAVHILTKDRFVSADRTYDVECKSSGSKPPALITWWKGSKQLKKLTKNFNEPDNQSL 354
                                        .|::.   ||...:|  ....|..|     :|:....
Human   169 ----------------------------SCEAG---PPLTFSW--TGNALSPL-----DPETTRS 195

  Fly   355 SILTFTPGREDDGKYLTCRAENQFIDGSAI--EDKWRLIVHYQPT-------------TTLKIGS 404
            |.||.||..||.|..|||:.:.|   |:.:  |...:|.|.|.|.             |.|:|.|
Human   196 SELTLTPRPEDHGTNLTCQVKRQ---GAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILS 257

  Fly   405 SLNPDDIKEGDDAYFECIVLANPKPYKMSWFHNGKEL---QHNISAGVILSDQSLVLQSVSRASA 466
            :.....|:||...:..|.|.:|| |..:|||..||.|   |.::|.       :|.|.::.....
Human   258 NGMSVPIQEGQSLFLACTVDSNP-PASLSWFREGKALNPSQTSMSG-------TLELPNIGAREG 314

  Fly   467 GDYTCLAVNSEGKGPSNPV--TLRIRYAPICATDHEE 501
            |::||...:..|....:.:  ..|...:.||.|:.::
Human   315 GEFTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQQ 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
side-IV	NP_001034052.2	V-set	79..188	CDD:284989	35/123 (28%)
		IG_like	80..188	CDD:214653	34/122 (28%)
		Ig	210..281	CDD:299845	6/70 (9%)
		Ig	319..392	CDD:299845	22/74 (30%)
		IG_like	319..383	CDD:214653	20/63 (32%)
		IG_like	412..489	CDD:214653	21/81 (26%)
		IGc2	413..478	CDD:197706	20/67 (30%)
		Ig_3	509..572	CDD:290638
		fn3	593..675	CDD:278470
SIGLEC14	NP_001092082.1	Ig_Siglec_N	21..140	CDD:143189	36/133 (27%)
		IG_like	26..139	CDD:214653	35/127 (28%)
		Ig	150..216	CDD:299845	24/166 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..209		8/18 (44%)
		Ig	252..335	CDD:299845	25/90 (28%)
		IG_like	261..336	CDD:214653	22/82 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000