DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment yrt and CSS1

DIOPT Version :9

Sequence 1:	NP_650291.1	Gene:	yrt / 41656	FlyBaseID:	FBgn0004049	Length:	972	Species:	Drosophila melanogaster
Sequence 2:	NP_012097.1	Gene:	CSS1 / 854637	SGDID:	S000001431	Length:	995	Species:	Saccharomyces cerevisiae

Alignment Length:	429	Identity:	84/429 - (19%)
Similarity:	177/429 - (41%)	Gaps:	49/429 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   549 YSPNATKNFDETNPFRNAT--SSHHGSFGKASISSGQLSVKSGLSDKDRELDSLLKSIVKD---- 607
            ||.:|...:     :.|:|  ||:..|....|.|||.:|:.|.:::.......:|.||.:.
Yeast    17 YSQSALGQY-----YSNSTSISSNSSSTSVVSSSSGSVSISSSIAETSSSATDILSSITQSASST 76

  Fly   608 --------PSPSVLANEAINDANSIRVTINKTFDMDHN---------TETLKRLSNANEKPNNQV 655
                    ||.|.:.:.:::.::|....::.:.....:         :::....|:.:...:...
Yeast    77 SGVSSSVGPSSSSVVSSSVSQSSSSVSDVSSSVSQSSSSASDVSSSVSQSASSTSDVSSSVSQSS 141

  Fly   656 KLANVNTTALPPGNIKCNILKARVEEELGAGGNAKLTNQMFVPAAHSSNMHTSNTNSSNNHAHSD 720
            ..|:..::::...:...:.:.:.|.:...:..:..       .:...|...||:.:||.:.:.|.
Yeast   142 SSASDVSSSVSQSSSSASDVSSSVSQSASSASDVS-------SSVSQSASSTSDVSSSVSQSSSS 199

  Fly   721 GPD-SLNATYISVGGDKLTLSIPEQKPST---GSSSSSSTSSTATTTTNGNGPYSNATFVSGFSA 781
            ..| |.:.:..|.....::.|:.:...||   .||.|.|.|||:..:::|:...|:|   ||.|:
Yeast   200 ASDVSSSVSQSSSSASDVSSSVSQSASSTSDVSSSVSQSASSTSGVSSSGSQSVSSA---SGSSS 261

  Fly   782 PLTPPSSLPANLNNTGSGCNTTLTSVTTISTPSSPTATVSTTASESVAPALSNASAAEI-LINEI 845
            ..  |.|..:....:||..:.:|:|:|:.::.:|.||:.|.::|:......:...:.:: |..::
Yeast   262 SF--PQSTSSASTASGSATSNSLSSITSSASSASATASNSLSSSDGTIYLPTTTISGDLTLTGKV 324

  Fly   846 FINNIINNNASGSITAETAAKPAGSSTPSA-GTLLFSTLSE-QERLESQKTNQQMNQSLNLNQNH 908
            .....:...|...:|.....|.:.|:.... |.||.....| ....|...:.:..:.:.|.|...
Yeast   325 IATEGVVVAAGAKLTLLDGDKYSFSADLKVYGDLLVKKSKETYPGTEFDISGENFDVTGNFNAEE 389

  Fly   909 SEVDAPPSEKKTPSNYPDSSRIPFPSSSNSKDMV--SPW 945
            |...:......|||::.:|..|....|.:.|..|  ||:
Yeast   390 SAATSASIYSFTPSSFDNSGDISLSLSKSKKGEVTFSPY 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yrt	NP_650291.1	B41	60..250	CDD:214604
		FERM_N	62..124	CDD:286467
		FERM_M	143..250	CDD:278785
		FERM_C_NBL4_NBL5	246..339	CDD:270007
		FA	352..392	CDD:285894
		PHA03255	771..>924	CDD:165513	33/155 (21%)
CSS1	NP_012097.1	Hyphal_reg_CWP	313..596	CDD:371712	23/116 (20%)
CSS1	NP_012097.1	PRK12355	627..>977	CDD:237072
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23280
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100