Protein Alignment yrt and frmd7

DIOPT Version :10

• Sequence 1: NP_650291.1
• Gene: yrt / 41656
• FlyBaseID: FBgn0004049
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: XP_017952463.2
• Gene: frmd7 / 779686
• XenbaseID: XB-GENE-6041331
• Length: 710
• Species: Xenopus tropicalis
• Alignment Length: 748
• Identity: 188/748 - (25%)
• Similarity: 292/748 - (39%)
• Gaps: 241/748 - (32%)

  Fly    61 RVILLDNTDLSIELSKKALGSFLYEQVFYALDIIEKDYFGLQFMDANHVKHWLDPTKPIKKQVKI 125
            :|..||::..:..:.:||.|..|:......|::.||:||||:|.:....:.||...|||.||||.
 Frog     5 KVQFLDDSQKTFVVDQKAPGKELFNMSCSHLNLTEKEYFGLEFRNHAGCQMWLGLLKPITKQVKH 69

  Fly   126 GPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRLDCPEDKATELCALALQSELGDYD 190
            .....|:..|||:..:|..|:.|||||||.||:|::|..|:|.|.::.|..:.:..|||||||::
 Frog    70 PKETIFKFMVKFFLVDPGLLKGELTRYLFALQIKKNLASGKLPCNDNSAALMASYVLQSELGDFE 134

  Fly   191 NQEHSAATVSEFRFVPEQTEDLEIAILDEYKTCRGLTPAQAETAFLNKAKWLDMYGVDMHTVLGK 255
             ::.:...:.:.:::|.| |.|:..||..|:...|.:||:::...|:.|:.||.||:..|.....
 Frog   135 -EDTARKHLEQNQYLPNQ-EYLDNKILKYYQRHVGKSPAESDMQLLDIARKLDTYGIRPHAASDG 197

  Fly   256 DGCEYHLGLTPTGILVFERDQKIGLFFWPKISKLDFKKKKLTLIVIEDDDEGREQEH-------T 313
            :|.:.:|.:...|:||...:.||..|.|..|.||.||:|...:         :...|       |
 Frog   198 EGMQINLAVAHMGVLVLRGNTKINTFNWANIRKLSFKRKHFLI---------KLHPHIDTLCKDT 253

  Fly   314 FVFRLYNEKACKHLWKCAVEHHTFFRL-RAPVKGPSARQNFFRMGSRFRYSGRTE---FQTTQQS 374
            .||.:.:..|||..||..||:|.|||| ..|.:.|  :......||.|||||||:   |.:..:.
 Frog   254 LVFTMESRDACKAFWKSCVEYHAFFRLSEEPKRKP--KPFLCSKGSNFRYSGRTQKQIFDSWTKG 316

  Fly   375 RARRTVQFERRPSQRFASRQSHL---LRERQKASQEAAVSAVA--------------------SV 416
            .: :.:.||||          ||   |.|||..|....::.||                    ||
 Frog   317 NS-KNLPFERR----------HLLANLHERQCRSSPDLLTEVAKQPNDFKLIYTSRPCSRSANSV 370

  Fly   417 --------NARAAAAAAAAAA-------SQSP-----------------------AP-------- 435
                    |.|.:|.....:|       ::.|                       ||
 Frog   371 GWDPPMHKNRRKSATEIIFSADLERSKPNEEPTILQLSKSSCSFPGCSYLDIKDNAPRTGYNKRP 435

  Fly   436 ------------------------ATPLVSS----QVSTPTPNNDNNNDAFDSLISTD------- 465
                                    |.||.|:    :|..|..::..|:|:.|.|..:|
 Frog   436 LSYYEDSKYFSGNFKSMSEGCMRDAAPLPSAIYTDRVPLPHSSHQLNSDSVDYLCYSDHLSSIPQ 500

  Fly   466 -------QFITVTPSPSVLTVIQNSAIIEPDA--------------ACSGSISSSSQAAANFA-- 507
                   :.:.:|..||  |.::.||...|.|              :|..|||...:..:...
 Frog   501 QTSAIVEEIVRLTNKPS--TFLEKSANRSPSARRIKEYHQPVYPRTSCRSSISMVPKRESQVTHV 563

  Fly   508 ----------SLGRNSLKSNFSNEDPAYSKIGSIG------KASGLTVK------------LDPD 544
                      ||..:.:||::.   |..|:...:|      |.|.::.:            |.|.
 Frog   564 EYTQDPYPKRSLSHSDMKSSWF---PCGSEFRPLGPCPILSKTSSISTRPLVPQHLPIPHQLPPP 625

  Fly   545 YTPPYSP-------------------NATKNFD-ET---NPFRNATSSHHGSFGKASISSGQLSV 586
            ..||.:|                   :.|::.| ||   ||:      ::..|||......::.:
 Frog   626 PPPPPAPPLPLTETKKVPRTTERYVYSGTESSDSETEIINPY------YYALFGKHRSPLTRIRL 684

  Fly   587 KSGLSDKDRELDSLLKSIVKDPSPSVLANEAIN 619
            .||....|.|                 .|.|||
 Frog   685 SSGSLQLDEE-----------------ENNAIN 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yrt	NP_650291.1	B41	60..250	CDD:214604	68/188 (36%)
		FERM_C_NBL4_NBL5	246..339	CDD:270007	30/99 (30%)
		FA	352..393	CDD:462582	14/43 (33%)
		PHA03255	771..>924	CDD:165513
frmd7	XP_017952463.2	FERM_F1_FRMD7	1..86	CDD:340708	28/80 (35%)
		FERM_B-lobe	94..184	CDD:271216	32/91 (35%)
		FERM_C_FARP1-like	179..299	CDD:270014	41/130 (32%)
		FA	294..327	CDD:462582	14/43 (33%)