Protein Alignment yrt and epb41l3

DIOPT Version :10

• Sequence 1: NP_650291.1
• Gene: yrt / 41656
• FlyBaseID: FBgn0004049
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: XP_017950527.2
• Gene: epb41l3 / 613048
• XenbaseID: XB-GENE-1006073
• Length: 1407
• Species: Xenopus tropicalis
• Alignment Length: 1193
• Identity: 291/1193 - (24%)
• Similarity: 451/1193 - (37%)
• Gaps: 323/1193 - (27%)

  Fly    42 GSSQI--KPQRIVVNKNKIDCRVILLDNTDLSIELSKKALGSFLYEQVFYALDIIEKDYFGLQFM 104
            |||::  .|.:.......:..:|:|||.::.|.|:.|::.|..|:|:|...|:::|||||||.:.
 Frog    92 GSSKLSKSPLKSARRPKNMQAKVMLLDGSEYSCEVEKRSKGQILFEKVCEHLNLLEKDYFGLVYR 156

  Fly   105 DANHVKHWLDPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRLDC 169
            |:.:.|:||||.|.||||.:.| .:.|...||||..:|:.|.|::|||...|||:.|::.|||.|
 Frog   157 DSENQKNWLDPAKEIKKQTRNG-AWHFSFNVKFYPPDPSQLSEDITRYYLCLQLRDDIVCGRLPC 220

  Fly   170 PEDKATELCALALQSELGDYDNQEHSAATVSEFRFVPEQTEDLEIAILDEYKTCRGLTPAQAETA 234
            .......|.:.::||||||||.:|:.:..|:||||.|.||::||..:::.:|:.||:|||:||..
 Frog   221 SFVTLALLGSYSVQSELGDYDPEEYGSDYVTEFRFAPNQTKELEDKVVELHKSYRGMTPAEAEMH 285

  Fly   235 FLNKAKWLDMYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKIGLFFWPKISKLDFKKKKLTLI 299
            ||..||.|.|||||:|.....:|.|..||:..:|:|::....:|..|.|||:.|:.:|:....:.
 Frog   286 FLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIK 350

  Fly   300 VIEDDDEGREQEHTFVFRLYNEKACKHLWKCAVEHHTFFRLRAPVKGPSARQNFFRMGSRFRYSG 364
            :...:.|  :.|.|..|:|.|.:|.|.|||..|||||||||..|...|   :.|..:||:|||||
 Frog   351 IRPGEFE--QFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLMPEAPP---KKFLTLGSKFRYSG 410

  Fly   365 RTEFQTTQQSRA--RRTVQFERRPSQRFASRQS---HLLRERQKASQEAAVSAVASVNARAAAAA 424
            ||:.||.:.|..  |....|||..|:|:...:|   ..:.|......:.:||| ..|.......|
 Frog   411 RTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGASVNENHDLYMKDSVSA-TEVGTGPYITA 474

  Fly   425 AAAAASQSPAPATPLVSSQ----------------VSTPTPNNDNNNDAFDSLISTDQFITVT-- 471
            ...:.:......||...::                .:..|..:|.....||    ||.|.:.:
 Frog   475 KGISQTNLITTVTPEKKAEEERDEEEEKKKKVEIITTVTTIRHDTKPSCFD----TDSFHSPSHP 535

  Fly   472 -PSPSV--------------------LTVIQNSAIIEP--DAACSG---------SISSSSQAAA 504
             .|||.                    |:...|....||  |:.|.|         :||...||
 Frog   536 HSSPSASSTKLRRRCKENARKAVGRELSKDVNEMSHEPERDSDCKGTLYPEEDELAISYKQQA-- 598

  Fly   505 NFASLGRNSLKSNFS----------NEDPAYSKIGSIGKASGLTVKLDPDYTPPYSPNATKNF-- 557
                 ||.....:||          .:|..|....:|.:.:.|...|. .|.|..||:....|
 Frog   599 -----GRGGTLFSFSLHLPDSFPSLLDDDGYLSFPNISETNFLPESLQ-HYLPIRSPSLVPCFLF 657

  Fly   558 -------------------------------------------------DETNPFRNATSSHHGS 573
                                                             |||:..:..|:
 Frog   658 IFFFLLSASFSVPYALTLSFPLAMCLCYLEPKAVSLSAALDNDLSDSSDDETDSEQTDTA----- 717

  Fly   574 FGKASISSGQLSVKSGLSDKDRELDSLLK---SIVK-------------------DPSPSVLANE 616
                  :.|:.:.    ::.|:|.|:..|   |::|                   |.:...|...
 Frog   718 ------ADGETTA----TESDQEEDTYAKTQNSLIKRIKGENVYVKHSNLMLEEFDRNQEELMKH 772

  Fly   617 AINDANSIRVTINKTFDMDHNTETLKRLSNA-------------------------NEKPNNQVK 656
            ..|.:...|..:..:.|.....|..||||.:                         .||...|:.
 Frog   773 QTNISELKRTFLETSTDTTTGGEWEKRLSTSPVRLVMRHEEAPMIEPLVPEETKEEREKREIQMS 837

  Fly   657 LANVNTTAL--PPGNIKCNILKARVEEELGAGGNAKLTNQMFVPAAH------------------ 701
            |...:.:.|  .||:|...:.:||....:..  :.::..|..:|.:.
 Frog   838 LERTSYSMLESQPGDIVKKLREARATSPVAT--SQQIIMQKTIPTSPEGTEDWVIIDKVPTKVVD 900

  Fly   702 --------------SSNMHTSNTNSS----------NNHAHSDGPDS------LNATYISVGGDK 736
                          ||:|......:|          .....|...||      |..:|.:|.|..
 Frog   901 GETKTIVTYKVTTVSSDMPAGTFKTSPLGGQSLDALKMELKSKEEDSKLKMYTLGRSYDTVSGKV 965

  Fly   737 LTLSI------PEQKPSTGSSSSSSTSSTATT--TTNGNGPYSNATFVS---GFSAPLTPP---- 786
            :|::.      .|:.||:...........|.|  ...|.|.|.....:|   |...|..||
 Frog   966 VTMTSKAKEGDKEKTPSSFEIIQKLEKDIAETIKIAPGTGDYEILEPISDDKGRKVPEGPPVKRR 1030

  Fly   787 -----SSLPANLNNTGSGCNTTLTSVTTISTPSSPTATVSTTASESV---------APALSNASA 837
                 :.:..:.:...|....||..|....|..:...:|....:|..         .|:..:...
 Frog  1031 MSETLTPIKESDSQLASPVEETLKKVQDKDTEKNLIESVIFGKAEQFQDYDVIKADVPSWKDKKL 1095

  Fly   838 AE--------------ILINEIFINNIINNNASGSITAETAAKPAGSSTPSAGTLLFSTLSEQER 888
            :|              ..:.|...:.::...:||..|.|      ||...|   ||.||....|.
 Frog  1096 SEWRYTRDQPFTIATAHYVTESSASKVVTKQSSGEKTLE------GSDIYS---LLESTRKPSEF 1151

  Fly   889 L-ESQKTNQQMNQSLNLNQNHSEVDAPPSEKKTPSNYPDSSRIPFPSSSNSKDMVSPWLVSSE-- 950
            | |...|:|...|                :.:|.:.:..||:....:...:|:.|...:||.|
 Frog  1152 LGEVTSTSQSWAQ----------------KTETTTEWDSSSKGQEDAEQKAKEKVVQGMVSLEES 1200

  Fly   951 -VVSAPKGRESAIIRKSVITTQL 972
             |.|....|::|.:..:||.:.|
 Frog  1201 LVGSVHASRDAAELAGTVIASSL 1223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yrt	NP_650291.1	B41	60..250	CDD:214604	88/189 (47%)
		FERM_C_NBL4_NBL5	246..339	CDD:270007	34/92 (37%)
		FA	352..393	CDD:462582	19/42 (45%)
		PHA03255	771..>924	CDD:165513	33/188 (18%)
epb41l3	XP_017950527.2	B41	112..301	CDD:214604	88/189 (47%)
		FERM_C_4_1_family	296..389	CDD:270005	36/94 (38%)
		FA	398..441	CDD:462582	19/42 (45%)
		SAB	758..806	CDD:461285	10/47 (21%)
		4_1_CTD	1293..1399	CDD:461774