Protein Alignment yrt and Frmd5

DIOPT Version :10

• Sequence 1: NP_650291.1
• Gene: yrt / 41656
• FlyBaseID: FBgn0004049
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: XP_038962754.1
• Gene: Frmd5 / 311362
• RGDID: 1561554
• Length: 599
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 160/545 - (29%)
• Similarity: 258/545 - (47%)
• Gaps: 99/545 - (18%)

  Fly    38 ITSGGSSQIKPQRIVVNKNKIDCRVILLDNTDLSIELSKKALGSFLYEQVFYALDIIEKDYFGLQ 102
            :.||.|..:        :.:..|.|.|||:::.:..:.:.|.|.:|::.:.:.|:::||||||::
  Rat     5 LMSGSSRSL--------EREYSCTVRLLDDSEYTCTIQRDAKGQYLFDLLCHHLNLLEKDYFGIR 61

  Fly   103 FMDANHVKHWLDPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRL 167
            |:|.:..:|||:.||.:.||::..||:|...:||||.::|..|:||:||||.|||:|:||..|||
  Rat    62 FVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRL 126

  Fly   168 DCPEDKATELCALALQSELGDYDNQEHSAATVSEFRFVPEQTEDLEIAILDEYKT-CRGLTPAQA 231
            .|....|..|.|..||:|:||||..:|.....|:|:|.|:.:|.||..|.:.:|| ..|.|||.:
  Rat   127 LCKTSDAALLAAYILQAEIGDYDPGKHPEGYSSKFQFFPKHSEKLEKKIAEIHKTELSGQTPATS 191

  Fly   232 ETAFLNKAKWLDMYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKI------------------ 278
            |..||.||:.|:.||||.|......|....|..||.|.:|.:.::::
  Rat   192 ELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFVVLQGNKRVHFIKCILFASFTAAIHWA 256

  Fly   279 GLF-----------FWPKISKLDFKKKKLTLIVIEDDDEGREQEHTFVFRLYNEKACKHLWKCAV 332
            |.|           .|.:::||.|:.|...|.|.:.:    |::....:.....:||||||||.:
  Rat   257 GGFKDFSTITPKPLSWNEVTKLKFEGKTFYLYVSQKE----EKKIILTYFAPTPEACKHLWKCGI 317

  Fly   333 EHHTFFRLR--APVKGPSARQNFFRMGSRFRYSGRTEFQTTQQSR--ARRTVQFERR-------- 385
            |:..|::|.  :.|:..|:...||: |||||||||...:..:.|.  .|...:..|.
  Rat   318 ENQAFYKLEKSSQVRTVSSSNLFFK-GSRFRYSGRVAKEVMESSAKIKREPPEIHRAGMVPSRSC 381

  Fly   386 PSQRFASRQSHLLRERQKASQEAAVSAVASV--------------------NARAAAA----AAA 426
            ||.....|.|.:.|.|::|...:.:..:.|:                    :.|::.|    ..|
  Rat   382 PSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSSSHGDTFLPHVRSSRADSNERVA 446

  Fly   427 AAASQSPAPATPLVSSQVSTPTPNNDNN----------NDAFDSLISTDQFITVTPSPSVLTVIQ 481
            ..|.::.:||..::      |||..:::          |.|..|:....:..|.||:.:....:.
  Rat   447 VIADEAYSPADSVL------PTPVAEHSLELMLLSRQINGATCSIEEEKESETSTPTSTEAEALG 505

  Fly   482 NSAIIEPDAACSGSISSSSQAAANF 506
            .    |..|.|.|...|..:....|
  Rat   506 G----ELRALCQGHGGSEQEQVNKF 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yrt	NP_650291.1	B41	60..250	CDD:214604	84/190 (44%)
		FERM_C_NBL4_NBL5	246..339	CDD:270007	30/121 (25%)
		FA	352..393	CDD:462582	16/50 (32%)
		PHA03255	771..>924	CDD:165513
Frmd5	XP_038962754.1	B41	19..210	CDD:214604	84/190 (44%)
		PH-like	191..324	CDD:473070	37/136 (27%)
		FA	338..383	CDD:462582	14/45 (31%)