Protein Alignment yrt and Epb41l2

DIOPT Version :10

• Sequence 1: NP_650291.1
• Gene: yrt / 41656
• FlyBaseID: FBgn0004049
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: XP_038954994.1
• Gene: Epb41l2 / 309557
• RGDID: 1563977
• Length: 1071
• Species: Rattus norvegicus
• Alignment Length: 866
• Identity: 232/866 - (26%)
• Similarity: 372/866 - (42%)
• Gaps: 146/866 - (16%)

  Fly    20 EGGGATSSAVGVAGGGGAITSGGSSQIKPQRIVVNKNKIDCRVILLDNTDLSIELSKKALGSFLY 84
            |||.|......|.      ||...:::..|:.......:..:|.|||.|:.|.:|.|:|.|..|:
  Rat   181 EGGAAKRETKEVQ------TSELKAEVASQKAAKKTKTVLAKVTLLDGTEFSCDLEKRAKGQALF 239

  Fly    85 EQVFYALDIIEKDYFGLQFMDANHVKHWLDPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREEL 149
            ::|...|:::|||||||.|.:....|:||||.|.||:|:: ..|:.|...||||..:|:.|.|::
  Rat   240 DRVCEHLNLLEKDYFGLIFQEHPEQKNWLDPAKEIKRQLR-SLPWLFTFNVKFYPPDPSQLTEDI 303

  Fly   150 TRYLFFLQLKQDLLEGRLDCPEDKATELCALALQSELGDYDNQEHSAATVSEFRFVPEQTEDLEI 214
            |||...|||:||:..|||.|.......|.:..||:|.||||.:|:.:..:.:|:|.|...::||.
  Rat   304 TRYFLCLQLRQDISSGRLPCSFVTHALLGSYTLQAEHGDYDPEEYDSIDLGDFQFAPTHNKELEE 368

  Fly   215 AILDEYKTCRGLTPAQAETAFLNKAKWLDMYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKIG 279
            .:.:.:||.|||:||||::.||..||.|.|||||:|.....:|.:..||:...|:|:::...:|.
  Rat   369 KVAELHKTHRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRIN 433

  Fly   280 LFFWPKISKLDFKKKKLTLIVIEDDDEGREQEHTFVFRLYNEKACKHLWKCAVEHHTFFRLRAPV 344
            .|.||||.|:.:|:....:.|...:.|  :.|.|..|:|.|.:|.|.|||..||||||:||.:|.
  Rat   434 RFAWPKILKISYKRSNFYIKVRPGELE--QFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPE 496

  Fly   345 KGPSARQNFFRMGSRFRYSGRTEFQTTQQSRA--RRTVQFERRPSQRFASR----------QSHL 397
            :.|..:  |..:||:|||||||:.||.:.|..  |...||||..|:| .||          ...|
  Rat   497 QPPKTK--FLTLGSKFRYSGRTQAQTREASTLIDRPAPQFERASSKR-VSRSLDGAPIGVVDQSL 558

  Fly   398 LRERQKASQEAAVSAVASVNARAAAAAAAAAASQSPAPATPLVS-SQVSTPTPNNDNNNDAFDSL 461
            :::......|.:|.....|:  ...........:||...|||:: .:.:|...:.||......:|
  Rat   559 MKDFPGPPGEGSVPGPGVVS--YTTVQDGRRDGKSPTKVTPLLAEGKKNTLRVDGDNIYVRHSNL 621

  Fly   462 ISTD--------------------QFITVTPSPSV-------LTVI--QNSAIIEPDAACSGSIS 497
            :..|                    .|:..||.|..       :|.:  |..|.:|.:..   ||.
  Rat   622 MLEDLDKAQEAILKHQASVSELKRNFMESTPEPRPSEWEKRRVTPLSCQILASLEEEIT---SIL 683

  Fly   498 SSSQAAANFASLGRNSLKSNFSNEDPAYSKIGSIGKASGLTVKLDPDYTPPYS-----PNATKNF 557
            .|.|..:       :|:|::|    |:.:...:.|.........:|..:.|:|     |.|..:.
  Rat   684 FSGQGFS-------HSVKASF----PSATTWTAEGTVVNANAPREPLSSAPFSRLPETPRALVSE 737

  Fly   558 DETNPFRNATSSHHGSFG------KASISSGQLSVKSGLSDKD----------RELDSLL----K 602
            ......|:|..|.|.:..      :|.:..|:..:...::.|:          |:::.:.    .
  Rat   738 GPCTGTRDAVKSSHETLNVVEEKKRAEVGKGESVITEEMNGKELSPGSGPGETRKVEPMAHKDST 802

  Fly   603 SIVKDPSPSVLANEAINDANSI----RVTINKTFDMDHNTETLKRLSNANEKPNNQVKLANVNTT 663
            |:..:.|.|  ::|:..|....    |||.....:.....|.|:      |:|....|:......
  Rat   803 SLSSESSSS--SSESEEDVGEYQPHHRVTEGTIREEQEYEEELE------EEPGQGAKVVEREAA 859

  Fly   664 ---ALPPGNIKCNILKARVEEE--------LGAGGNAKLTNQMFVPAAHSSNMHTSNTNSSNNHA 717
               |:|......::|....|.:        .|..|..:.|.:..:......:.|  ..|....|.
  Rat   860 MPEAIPDRQAGASVLPVETEAQENVVAQKLPGEKGAHRGTAEQDMSEEAEEDQH--RVNGEVPHL 922

  Fly   718 HSDG--------------------PDSLNATYIS------VGGDKLTLSIPEQKPSTGSSSSSST 756
            ..||                    .|:...|.||      |..:..|::....:...|:...|..
  Rat   923 DIDGLPEIVCPSEPPVVKTEMVTISDASQRTEISTKEVPIVQTETKTITYESPQIDGGAGGDSGV 987

  Fly   757 SSTATTTTNGNGPYSNATFVS 777
            ..||.|.|:.:...:..|.::
  Rat   988 LLTAQTITSESASTTTTTHIT 1008

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yrt	NP_650291.1	B41	60..250	CDD:214604	84/189 (44%)
		FERM_C_NBL4_NBL5	246..339	CDD:270007	35/92 (38%)
		FA	352..393	CDD:462582	20/42 (48%)
		PHA03255	771..>924	CDD:165513	1/7 (14%)
Epb41l2	XP_038954994.1	PTZ00121	<4..>216	CDD:173412	8/40 (20%)
		B41	215..404	CDD:214604	84/189 (44%)
		FERM_C_4_1_family	399..492	CDD:270005	36/94 (38%)
		FA	502..545	CDD:462582	21/45 (47%)
		SAB	622..662	CDD:461285	5/39 (13%)
		4_1_CTD	958..1064	CDD:461774	9/51 (18%)