Protein Alignment yrt and Frmd5

DIOPT Version :10

• Sequence 1: NP_650291.1
• Gene: yrt / 41656
• FlyBaseID: FBgn0004049
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: XP_011237768.1
• Gene: Frmd5 / 228564
• MGIID: 2442557
• Length: 599
• Species: Mus musculus
• Alignment Length: 536
• Identity: 159/536 - (29%)
• Similarity: 258/536 - (48%)
• Gaps: 106/536 - (19%)

  Fly    38 ITSGGSSQIKPQRIVVNKNKIDCRVILLDNTDLSIELSKKALGSFLYEQVFYALDIIEKDYFGLQ 102
            :.||.|..:        :.:..|.|.|||:::.:..:.:.|.|.:|::.:.:.|:::||||||::
Mouse     5 LMSGSSRSL--------EREYSCTVRLLDDSEYTCTIQRDAKGQYLFDLLCHHLNLLEKDYFGIR 61

  Fly   103 FMDANHVKHWLDPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRL 167
            |:|.:..:|||:.||.:.||::..||:|...:||||.::|..|:||:||||.|||:|:||..|||
Mouse    62 FVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRL 126

  Fly   168 DCPEDKATELCALALQSELGDYDNQEHSAATVSEFRFVPEQTEDLEIAILDEYKT-CRGLTPAQA 231
            .|....|..|.|..||:|:||||..:|.....|:|:|.|:.:|.||..|.:.:|| ..|.|||.:
Mouse   127 LCKTSDAALLAAYILQAEIGDYDPGKHPEGYSSKFQFFPKHSEKLEKKIAEIHKTELSGQTPATS 191

  Fly   232 ETAFLNKAKWLDMYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKI------------------ 278
            |..||.||:.|:.||||.|......|....|..||.|.:|.:.::::
Mouse   192 ELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFVVLQGNKRVHFIKCILFASFTAAIHWA 256

  Fly   279 GLF-----------FWPKISKLDFKKKKLTLIVIEDDDEGREQEHTFVFRLYNEKACKHLWKCAV 332
            |.|           .|.:::||.|:.|...|.|.:.:    |::....:.....:||||||||.:
Mouse   257 GGFKDFSTITPKPLSWNEVTKLKFEGKTFYLYVSQKE----EKKIILTYFAPTPEACKHLWKCGI 317

  Fly   333 EHHTFFRLR--APVKGPSARQNFFRMGSRFRYSGRTEFQTTQQSR--ARRTVQFERR-------- 385
            |:..|::|.  :.|:..|:...||: |||||||||...:..:.|.  .|...:..|.
Mouse   318 ENQAFYKLEKSSQVRTVSSSNLFFK-GSRFRYSGRVAKEVMESSAKIKREPPEIHRAGMVPSRSC 381

  Fly   386 PSQRFASRQSHLLRERQKASQEAAVSAVASVNARAAAAAAAAAASQSPAPATPLVSSQVSTPTPN 450
            ||.....|.|.:.|.|::|...:.:..:.|:              :..|.:||:.||
Mouse   382 PSITHGPRLSSVPRTRRRAVHISIMEGLESL--------------RDSAHSTPVRSS-------- 424

  Fly   451 NDNNNDAF-----DSLISTDQFITV------TPSPSVL--TVIQNS--------------AIIEP 488
              ::.|.|     .|...:::.:.|      :|:.|||  .|.::|              ..||.
Mouse   425 --SHGDTFLPHVRSSRADSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEE 487

  Fly   489 DAACSGSISSSSQAAA 504
            :.....|..::::|.|
Mouse   488 EKESEASTPTATEAEA 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yrt	NP_650291.1	B41	60..250	CDD:214604	84/190 (44%)
		FERM_C_NBL4_NBL5	246..339	CDD:270007	30/121 (25%)
		FA	352..393	CDD:462582	16/50 (32%)
		PHA03255	771..>924	CDD:165513
Frmd5	XP_011237768.1	B41	19..210	CDD:214604	84/190 (44%)
		PH-like	191..324	CDD:473070	37/136 (27%)
		FA	338..383	CDD:462582	14/45 (31%)