Protein Alignment yrt and Epb41l3

DIOPT Version :10

• Sequence 1: NP_650291.1
• Gene: yrt / 41656
• FlyBaseID: FBgn0004049
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: XP_006523675.1
• Gene: Epb41l3 / 13823
• MGIID: 103008
• Length: 1425
• Species: Mus musculus
• Alignment Length: 1102
• Identity: 263/1102 - (23%)
• Similarity: 423/1102 - (38%)
• Gaps: 254/1102 - (23%)

  Fly    43 SSQI--KPQRIVVNKNKIDCRVILLDNTDLSIELSKKALGSFLYEQVFYALDIIEKDYFGLQFMD 105
            ||::  .|.:||.....:.|:|.|||.::...::.|::.|..|:::|...|:::|||||||.:.|
Mouse   101 SSKLSRSPLKIVKRPKSMQCKVTLLDGSEYGCDVDKRSRGQVLFDKVCEHLNLLEKDYFGLTYRD 165

  Fly   106 ANHVKHWLDPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRLDCP 170
            |.:.|:||||.|.||||::.| .:.|...||||..:|..|.|::|||...|||:.|::.|||.|.
Mouse   166 AENQKNWLDPAKEIKKQIRSG-AWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCS 229

  Fly   171 EDKATELCALALQSELGDYDNQEHSAATVSEFRFVPEQTEDLEIAILDEYKTCRGLTPAQAETAF 235
            ......|.:..:||||||||..|.....:|||||.|..|::||..:::.:|:.||:|||:||..|
Mouse   230 FVTLALLGSYTVQSELGDYDPDECGNDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHF 294

  Fly   236 LNKAKWLDMYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKIGLFFWPKISKLDFKKKKLTLIV 300
            |..||.|.|||||:|.....:|.|..||:..:|:|::....:|..|.|||:.|:.:|:....:.:
Mouse   295 LENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKI 359

  Fly   301 IEDDDEGREQEHTFVFRLYNEKACKHLWKCAVEHHTFFRLRAPVKGPSARQNFFRMGSRFRYSGR 365
            ...:.|  :.|.|..|:|.|.:|.|.|||..|||||||||..|...|   :.|..:||:||||||
Mouse   360 RPGEFE--QFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPP---KKFLTLGSKFRYSGR 419

  Fly   366 TEFQTTQQSRA--RRTVQFERRPSQRFASRQSHLLRERQKASQEAAVSAVASVNARAAAAAAAAA 428
            |:.||.:.|..  |....|||..|:|:...:|         ...|:||....:..:.:.:||...
Mouse   420 TQAQTRRASALIDRPAPYFERSSSKRYTMSRS---------LDGASVSENHEIYMKDSVSAAEVG 475

  Fly   429 ASQSPAPATPLVSSQVSTPTPNNDNNNDAFDSLISTDQFITVTPSPSVLTVIQNSAIIEPDAACS 493
            ..|.........::.::|.||......:..:......:....||    :|.:::.....|....:
Mouse   476 TGQYATTKGISQTNLITTVTPEKKAEEERVEEEDRRKKAEEATP----VTALRHEGKSPPGHGAA 536

  Fly   494 GSISSSSQAA-------------------ANFASLGRNSL-KSNFSNEDPAYSKIGSIGKASGL- 537
            .|...|..:|                   |..:||...:. |:...::|.|:|.....||.:.|
Mouse   537 DSCPPSPPSAHPDPPPPTELRRRCKEKERAEPSSLESEAQGKAYLGDQDVAFSYRQPAGKGTTLF 601

  Fly   538 ----------TVKLDPD--------------------------------------------YTPP 548
                      ...||.|                                            ::.|
Mouse   602 SFSLQLPESFPSLLDEDGYLSFPNLSETNLLPQSWQHFLPIRSPSLLPCFLFIFFFLLSASFSVP 666

  Fly   549 Y--------------------SPNATKNFDETNPFRNATSSHHGSFGKASISSGQLSVKSGLSDK 593
            |                    |.:|:.:.|.::.....|.|....    :.:.|:.|......::
Mouse   667 YALTLSFPLALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTD----TAADGETSATESDQEE 727

  Fly   594 DREL---DSLLKSIVKDPSPSVLANEAINDANSIRVTINKTFD--MDHNTETLKRLSNANEKPNN 653
            |.|:   :||:|.|..:       |..:..:|.:...::||.|  |.|.| .:..|.....:.:.
Mouse   728 DAEIKAQNSLIKRIKGE-------NVYVKHSNLMLEDLDKTQDELMKHQT-NISELKRTFLETST 784

  Fly   654 QVKLANVNTTALPPGNIKCNILKARVEEELGAGGNAKLTNQMFVPAAHSSNMHTSNTNSSNNHAH 718
            :..|.|.....|....::   |.||.|:       |.:...: ||.........|.
Mouse   785 ETALTNEWEKRLSTSPVR---LAARQED-------APMIEPL-VPEETKEEREISE--------- 829

  Fly   719 SDGPDSLNATYISVGGDKLTLSIPEQKPSTGSSSSSSTSSTATTTTNGNGPYSNATFVSGFSAPL 783
                   ...::..|.....    |.:||....:....|:.:..||:                .:
Mouse   830 -------KVVFLQQGSSPFL----ESQPSVTEKTQEGVSADSVATTH----------------QI 867

  Fly   784 TPPSSLPANLNNTGSGCNTTLTSVTTISTPSS-----PTATVSTTASESVAPALSNAS------- 836
            ....::|:.|..|.............:...|.     ...|||:...|..|..|.:..
Mouse   868 IFQKTVPSTLEGTEDWVIVDKIPTEVVDGDSKKIVTYKVVTVSSKTGEIPADLLKSGMMDMHGFD 932

  Fly   837 --AAEILINE-----IFINNIINNNASGSITAETAAKPAGSSTPSAGTL---------------L 879
              ..|:.:.|     |:......:..||.|...|.....|...|...||               :
Mouse   933 DLTREMQLKEENKQKIYTLGKSYDTVSGRIVTMTGKAKDGEKGPQLSTLEGLQKMERGASEAVRV 997

  Fly   880 FSTLSEQERLE------SQKTNQQMNQSLNLNQNHSEVDAPPSEKKTPSNYPDSSRIP------- 931
            ...|.|.|.||      |::..:.......|:::.:.:....|.:::|.. .|:.:.|
Mouse   998 GPLLVEYEVLEALTDEKSRRAPEVQTPKRRLSESLAPIKEAESRRQSPEE-DDTQKAPKLGDYAP 1061

  Fly   932 -FPSSSNS-----------------KDMVSPWLVSSE----VVSAPKGRESAIIRKSVITTQ 971
             .|..|.:                 :..:|.|..|.|    |.:|....||:  ...|:|.|
Mouse  1062 AHPQFSKTQQEPECKVLKVGPFGPRRKSLSEWRYSHEPAFTVATAHYVTESS--ASQVVTKQ 1121

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yrt	NP_650291.1	B41	60..250	CDD:214604	86/189 (46%)
		FERM_C_NBL4_NBL5	246..339	CDD:270007	34/92 (37%)
		FA	352..393	CDD:462582	19/42 (45%)
		PHA03255	771..>924	CDD:165513	30/192 (16%)
Epb41l3	XP_006523675.1	B41	120..309	CDD:214604	86/189 (46%)
		FERM_C_4_1_family	304..397	CDD:270005	36/94 (38%)
		FA	406..449	CDD:462582	19/42 (45%)
		SAB	754..802	CDD:461285	10/48 (21%)
		4_1_CTD	1311..1417	CDD:461774