Protein Alignment yrt and Cdep

DIOPT Version :10

• Sequence 1: NP_650291.1
• Gene: yrt / 41656
• FlyBaseID: FBgn0004049
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: XP_061507862.1
• Gene: Cdep / 1281890
• VectorBaseID: AGAMI1_011673
• Length: 4743
• Species: Anopheles gambiae
• Alignment Length: 1187
• Identity: 272/1187 - (22%)
• Similarity: 447/1187 - (37%)
• Gaps: 321/1187 - (27%)

  Fly    15 VDNSREGGGATSSAVGVAGGGGAITS-------GGSSQIKPQRIVVNKNKIDCRVILLDNTDLSI 72
            :|:.....|..||.||...|...|.|       .|:......|   ...|:..|:.:||::....
Mosquito     3 LDSMGPSAGGGSSGVGTLSGTRMIHSLSTPSGVDGTVSTSHSR---GGKKLAVRIQMLDDSVTMF 64

  Fly    73 ELSKKALGSFLYEQVFYALDIIEKDYFGLQFMDA-NHVKHWLDPTKPIKKQVKIG--PPYTFRLK 134
            ::..||.|..|:|||...|:::|.|||||::.:| :..|:|||..|.:.:||.:.  .| ..|..
Mosquito    65 QVQAKATGKVLFEQVCRQLNLLEADYFGLEYQEAPSGTKYWLDLEKSLNRQVGLSLVEP-VLRFC 128

  Fly   135 VKFYSSEPNTLREELTRYLFFLQLKQDLLEGRLDCPEDKATELCALALQSELGDYDNQEHSAAT- 198
            ||||:.:|..|.||.|||||.||:|:||..|.|.|.::.|..:.:..:|:..|||..:::...|
Mosquito   129 VKFYTPDPLQLEEEYTRYLFCLQVKRDLATGSLQCNDNTAALMASYIVQASCGDYAAEDYPDHTY 193

  Fly   199 VSEFRFVPEQTEDLEIAILDEYKTCRGLTPAQAETAFLNKAKWLDMYGVDMHTVLGKDGCEYHLG 263
            :|.:||||:|...::..|::.:|...|.:||:|:...|..|:..::||:.||.....||...:|.
Mosquito   194 LSSYRFVPQQDHTMQRRIMENHKKHVGQSPAEADLNLLETARRCELYGMKMHPAKDHDGVPLNLA 258

  Fly   264 LTPTGILVFERDQKIGLFFWPKISKLDFKKKKLTLIVIEDDDEGREQEHTFVFRLYNEKACKHLW 328
            :...||.||:...:|..|.|.||.|:.||:|:..:.:..::....:....|.|...||  ||:.|
Mosquito   259 VAHMGIAVFQGITRINTFSWAKIRKISFKRKRFLIKLHPENYVYHKDTVEFFFEGRNE--CKNFW 321

  Fly   329 KCAVEHHTFFRLRAPVKGPSARQNFFRMGSRFRYSGRT-----EF--------QTTQQSRARR-- 378
            |..||:|.|||..|.......:......||.|||||:|     ||        ||.|:|::.|
Mosquito   322 KKCVENHGFFRCTAVQNVQRRKARVLSRGSSFRYSGKTQKQIIEFVRDNYVKRQTFQRSQSFRQG 386

  Fly   379 -----------------------------TVQFERRPSQRFASRQSHLLRERQKASQEAAVSA-- 412
                                         |.::|||       .||::||...:..::..:..
Mosquito   387 PLHSSNRSQSRTSCNVNQSISAHPLLPIETAEWERR-------SQSNVLRTPSQTRRQVDMEVDR 444

  Fly   413 -VASVNARAAAAAAAAAASQSPAPA------------TPLV-SSQVSTP-----TPNNDNNN--- 455
             .:|....:.:....|.....|..:            |||. |||.::|     :|.:::|:
Mosquito   445 LPSSPTGHSRSQLTEAQVETYPMKSYTQQMGMEGSGHTPLQDSSQSASPGGTWSSPYHNSNSSHA 509

  Fly   456 ----------DAFDSLISTDQFITVTPS------------------------------------- 473
                      |...|.::...:.|::|.
Mosquito   510 READRARARQDGHSSGLNHRLYATMSPKYTHRSHRFTTQPQQLLQQPQQQQQRRASAGPLGQPGD 574

  Fly   474 ---------------PSVL----TVIQNSAIIEPDAACSGSISSSSQAAANFASLGRNSLKSNFS 519
                           .|||    |..:.|:.:.|..|.|||..:.|...|:.:.....:| :.:|
Mosquito   575 RSSSMGETTVSSTSRESVLLPLDTRTRRSSALLPGVAASGSGMAPSMVGASSSQYPSATL-ARYS 638

  Fly   520 NEDPAYSKIGSIGKASGLTVKLDPDYTPP---YSPNATKNFDETNPFRNATSS--HHGSFGKASI 579
            |.. .||...|:...:.|:     |..|.   ||     :.::....|.:|:|  ..|..|..|.
Mosquito   639 NTS-TYSMSKSVSTGTDLS-----DEAPDNVIYS-----DINDLYRHRKSTTSGGSGGGGGGGSA 692

  Fly   580 SSGQLSVKSG------LSDKDRELDSLLKSIVKDPS----PSVLANEAINDANSIR--------- 625
            |..:.:..:.      :.|.|..:|.     |:|.:    |.:..::..:|...||
Mosquito   693 SEARTNAAADEEAAEEVEDDDEIMDE-----VEDENAIRRPYLEDDDDDDDEIDIRYATATQIKA 752

  Fly   626 VTINKTFD-------------MDHNTETLKRLSNANEKPNNQ----VKLANVNTTALPPG----- 668
            :|.....|             :|..::..|:|....::...|    |::|.:.|....||
Mosquito   753 MTSGAASDAPKPVPSDELYATVDRKSKLNKQLQQQQQQQQQQQQVTVQVATLKTNTHYPGKHFSD 817

  Fly   669 --------------NIKCNILKARVEEELGAGGNAKLTNQMFVPAAH----SSNMHTSNT----- 710
                          ||..|:  :::.:..|...|:....:|:..:||    ..|...|:|
Mosquito   818 EFIDDSIRNYNSHTNISTNV--SKLNDASGGTLNSASAGEMYNRSAHFDEYCGNNRYSDTSDYFS 880

  Fly   711 NSSNNHAHSDGPDSLNATYISVGG-----DKLTLSIPEQ-KPSTGSSSSSSTSSTATTTTNGN-- 767
            :|..:::||....||..|.....|     |:.:.|.|.. .|.|..|...::......:.:.|
Mosquito   881 HSQQHYSHSPNSQSLATTITHKNGLTDDDDRYSCSNPPPIHPRTSHSLPRNSQLAKIESIDSNYS 945

  Fly   768 ----GPYSNA---------TFVSGFSAPLTPPSSLPAN--------LNNTGSGCNTTLTSVTTIS 811
                ||.|..         .|:...|....|.||...|        |...|:|          ..
Mosquito   946 GGEGGPSSGGRTGGSSGEHNFMGHHSLNNLPSSSKVTNDYLHYSSLLKGGGAG----------DG 1000

  Fly   812 TPSSPTATVSTTASESVAPALSNASA---------AEILINEIFINNIINNNASGSITAETAAKP 867
            .|..|..: ..|:||.:...||||:.         .|....|.::|......|....:.|...:.
Mosquito  1001 GPDDPMNS-KKTSSERLEYELSNANIYSTVQYKNYEEDFDEEEYMNYQRQRGADRDASKEAWLRS 1064

  Fly   868 AGSST------PSAGTLLFSTLSEQ----ERLESQKTN----------QQMNQSLNLNQNHSEVD 912
            :....      .|.|...||.:..:    :|::|..|.          |:.|.|:.::|     |
Mosquito  1065 SSCKELCDYGYDSTGRADFSLMEREFLTSDRIDSPVTRYDDSRHSMYVQKSNYSVEVSQ-----D 1124

  Fly   913 APPSEKKT-PSNYPDSS 928
            ...:|.|. .|:||.::
Mosquito  1125 CLANEGKVYSSSYPGTT 1141

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yrt	NP_650291.1	B41	60..250	CDD:214604	70/193 (36%)
		FERM_C_NBL4_NBL5	246..339	CDD:270007	31/92 (34%)
		FA	352..393	CDD:462582	19/84 (23%)
		PHA03255	771..>924	CDD:165513	39/199 (20%)
Cdep	XP_061507862.1	None