Protein Alignment yrt and epb41l4b

DIOPT Version :10

• Sequence 1: NP_650291.1
• Gene: yrt / 41656
• FlyBaseID: FBgn0004049
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: XP_005158090.1
• Gene: epb41l4b / 100332627
• ZFINID: ZDB-GENE-100921-92
• Length: 729
• Species: Danio rerio
• Alignment Length: 849
• Identity: 304/849 - (35%)
• Similarity: 401/849 - (47%)
• Gaps: 211/849 - (24%)

  Fly     1 MLRFL----SRRKVRNNYVDNSREGGGATSSAVGVAGGGGAITSGGSSQIKPQRIVV-------- 53
            |:.||    |||..||....:..:|       .|...||.|:......|:.....||
Zfish     1 MMGFLRRTFSRRSKRNARPPSEVDG-------TGNVRGGNAVLQAHQQQVIHAPTVVTGGAVVHI 58

  Fly    54 -----NKNKIDCRVILLDNTDLSIELSKKALGSFLYEQVFYALDIIEKDYFGLQFMDANHVKHWL 113
                 :|:.|.|||:|||.:|:::||.|.|.|..|::|:.|.||::|.|||||||||...|.|||
Zfish    59 PAAGNSKDAITCRVLLLDGSDVNVELPKHAKGQDLFDQIMYHLDLVEADYFGLQFMDPEQVAHWL 123

  Fly   114 DPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRLDCPEDKATELC 178
            |..||||||::.||||....:|||||||||.|.||.|||||.|||:||:|.|:|.||.|.:.||.
Zfish   124 DAAKPIKKQIRHGPPYRLFFRVKFYSSEPNNLHEEFTRYLFVLQLRQDILSGKLKCPYDVSVELG 188

  Fly   179 ALALQSELGDYDNQEHSAATVSEFRFVPEQTEDLEIAILDEYKTCRGLTPAQAETAFLNKAKWLD 243
            |..|||||||.|..|||...||||||.|:|||.:|..|..::..|||:.|:|||..||||.|||:
Zfish   189 AYCLQSELGDCDPLEHSILLVSEFRFSPKQTEIMEADIYRKWVECRGMIPSQAELNFLNKCKWLE 253

  Fly   244 MYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKIGLFFWPKISKLDFKKKKLTLIVIEDDDEGR 308
            |||||||.|.|:||.||.||||||||||||...||||||||||::||||:.:|||:|:|||::||
Zfish   254 MYGVDMHFVKGRDGGEYALGLTPTGILVFEGSSKIGLFFWPKITRLDFKRNRLTLVVVEDDEKGR 318

  Fly   309 EQEHTFVFRLYNEKACKHLWKCAVEHHTFFRLRAPVKGPSARQNFFRMGSRFRYSGRTEFQTTQQ 373
            ||||||||:|.:...||||||||||.|.|||||.|....::|.:|.|:|||||:|||||:|.|..
Zfish   319 EQEHTFVFQLSSSHECKHLWKCAVESHAFFRLRQPTHNKTSRSDFTRLGSRFRFSGRTEYQATHS 383

  Fly   374 SRARRTVQFERRPSQRFASRQSHLLRERQKASQEAAVSAVASVNARAAAAAAAAAASQSPAPATP 438
            .:.||...||||||:|:.||                  |.:.|.|...|.....:|..||.|:..
Zfish   384 GKVRRASTFERRPSKRYPSR------------------AQSMVKAMTPAKHPHLSAQTSPEPSLK 430

  Fly   439 LVSSQVSTPTPNNDNNNDAFDSLISTDQFITVTPSPSVLTVIQNSAIIEPDAACSGSISSSSQAA 503
            .....:.                |:.|.:....|.||:.:
Zfish   431 PYKHNIP----------------IAQDPWQRSHPPPSLTS------------------------- 454

  Fly   504 ANFASLGRNSLKSNFSNEDPAYSKIGSIGKASGLTVKLDPDYTPPYSPNATKNFD-ETNPFRNAT 567
                               |.|.:...:|..       .|.::.|.|...|:.|. |.|   .|.
Zfish   455 -------------------PLYIQPMELGHT-------PPPHSFPLSAADTRRFSVEEN---EAP 490

  Fly   568 SS-------HHGSFGK------ASISSGQLSVKSGLSDK-DRELDSLLKSIVKDPS--PSVLANE 616
            .|       ||..:.|      .:.......|...|||: ||.|.:.|::   :|:  |::..|
Zfish   491 HSGKIHRCYHHHGYEKQEPLCLTTAKPKAWVVSPALSDELDRALQNQLEA---EPAAWPALHIN- 551

  Fly   617 AINDANSIRVTINKTFDMDHNTETLKRLSNANEKPNNQVKLANVNTTALPPGNIKCNILKARVEE 681
                           .||            |.|||.::..|.  ::.|:....:|.||.|...:.
Zfish   552 ---------------IDM------------AEEKPLSEKSLP--SSPAVLQEQLKSNISKRATQS 587

  Fly   682 ELG-AGGNAKLTNQMFVPAAHSSNMHTSNTNSSN----------------NHAHSDGPDSLNATY 729
            :.| :.||:...:|   ...:.|:...|.::|.|                :..|||..|
Zfish   588 DSGNSKGNSSSGDQ---TDRYPSSSQDSGSSSLNIEKPRVDRRKRLVRQFSFNHSDEDD------ 643

  Fly   730 ISVGGDKLTLSIPEQKPSTGSSSSSSTSSTATTTTNGNGPYSNATFVSGFSAPLTPPSSLPANLN 794
                       :||...:..|..|...||            ||::.......|:.||....:.|.
Zfish   644 -----------LPEALAAISSQCSMGKSS------------SNSSLDKQVQPPIYPPQKDTSRLE 685

  Fly   795 NTGS 798
            :..|
Zfish   686 HDSS 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yrt	NP_650291.1	B41	60..250	CDD:214604	115/189 (61%)
		FERM_C_NBL4_NBL5	246..339	CDD:270007	67/92 (73%)
		FA	352..393	CDD:462582	23/40 (58%)
		PHA03255	771..>924	CDD:165513	7/28 (25%)
epb41l4b	XP_005158090.1	B41	69..260	CDD:214604	115/190 (61%)
		FERM_C_NBL4_NBL5	256..349	CDD:270007	67/92 (73%)
		FA	362..403	CDD:462582	23/40 (58%)