DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir87a and grid1a

DIOPT Version :9

Sequence 1:	NP_650290.2	Gene:	Ir87a / 41654	FlyBaseID:	FBgn0038153	Length:	796	Species:	Drosophila melanogaster
Sequence 2:	XP_021323097.1	Gene:	grid1a / 793756	ZFINID:	ZDB-GENE-120411-28	Length:	1044	Species:	Danio rerio

Alignment Length:	405	Identity:	84/405 - (20%)
Similarity:	145/405 - (35%)	Gaps:	74/405 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   408 KLSGIEYEMVQTIAERLHVSIEMQGENSNLYHLFQQLIDGEIEMIVGGIDEDPSISQFVSSSIPY 472
            |:.|.:|||.| :|:..:.|.:..|..:.   :..:||....::.:..|...|.....|..|..|
Zfish   477 KILGFKYEMYQ-VADAKYGSPQTNGSWNG---MIGELIGKRADVAISAITITPERENVVDFSKRY 537

  Fly   473 HQDELTWCVARAKRRHGFFNFVATFNADAGFLIGIFVVTCSLVVWLAQRVSGFQLRNLNG-YFPT 536
            ....:...:.:.:.|...|:.:|.|:......|...:....::|:|.:||...:.:|..| :.|.
Zfish   538 LDYSVGILMTKTEERLNIFSLLAPFDLAVWACIAAAIPVVGVMVFLLRRVQSVRSQNPPGPHQPA 602

  Fly   537 CLR---------VLGILLNQAIPAQDFPITLRQLFALSFLMGFFFSNTYQSFLISTLTTPRSSYQ 592
            .:.         |.|..:.|...:....:.||......:|......::|.:.|.:.||..|....
Zfish   603 SVTTSFQSAIWIVYGAFVQQGGESFMSSMALRIAMGSWWLFTLIVCSSYTANLAAYLTVSRMDNA 667

  Fly   593 IHTLQEIYSNKMTVMGTSEHVRHLNKDGEIFKYIREK----FQMCYNLVDCLNDAAQNEHIAVAV 653
            |.|.|::........||.       ::..:|:|.|.|    .:......:......:|:
Zfish   668 IRTFQDLSKQSEINYGTV-------RESAVFEYFRVKGTNPLEQDSTFAELWRTINKNQ------ 719

  Fly   654 SRQHSFYNP-----RIQRDRLYCF--DRRESLYVYLV----TMLL------PKKYHLLHQ----- 696
            .:.:|..:|     :::||. |.|  |.....|..|.    |:::      .|.|.|..|
Zfish   720 GQDNSVTSPAEGIRKVKRDP-YAFLWDMAVLEYAALTDDDCTLVVTGNGMSSKGYGLALQHGSPY 783

  Fly   697 ---INPVIQHIIESGHM----QKW-----ARDLDMRRMIHEEITRVREDPFKALTFDQFRGAIAF 749
               .:..|..:.|.|.:    |||     ..|||.    |.|    .:...:||....|.|....
Zfish   784 RDLFSQKILDLQEKGDLDILKQKWWPRKGRCDLDK----HAE----PQTEGRALRLHSFAGVFCI 840

  Fly   750 SGGLLLVASCVFAFE 764
            ....||:|..|.|.|
Zfish   841 LAAGLLLACLVAALE 855

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir87a	NP_650290.2	Periplasmic_Binding_Protein_Type_2	408..>475	CDD:304360	16/66 (24%)
grid1a	XP_021323097.1	Periplasmic_Binding_Protein_Type_1	25..424	CDD:324556
		PBP2_iGluR_delta_1	437..809	CDD:270448	69/349 (20%)
		DNA_pol3_gamma3	<915..1044	CDD:331207
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910